A83-01
Référence bs-82179C-5mg
Conditionnement : 5mg
Marque : Bioss
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| Overview | |
| Catalog # | bs-82179c-5mg |
| Product Name | A83-01 |
| Specifications | |
| Storage Buffer | Light yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Potent and selective ALK4, 5 and 7 inhibitor1,2. IC50=45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFβ2. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency3. Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts4. Cell permeable. Active in vivo. |
| Description | CAS Number: 909910-43-6 Chemical Name: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide Molecular weight: 421.53 Formula: C25H19N5S Solubility: DMSO (20 mg/ml) Physical Properties: Light yellow solid Purity: 98% by TLC, NMR (Conforms) |
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