ACAT1 Antibody

Référence MBS857958-0,1mL-PE

Conditionnement : 0.1mL(PE)

Marque : MyBiosource

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ACAT1 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS857958

MBS857958 is an antibody targeting ACAT1. Also known as ACAT1 Antibody. Reactive in Human, Mouse, Rat. More details

Product Overview

Online Datasheet in PDF
Product Name
ACAT1, Antibody
Full Product Name
ACAT1 Antibody
Product Gene Name
anti-ACAT1 antibody
Product Synonym Names
ACAT; acetoacetyl coenzyme A thiolase; acetoacetyl-CoA thiolase; acetyl-CoA acetyltransferase,mitochondrial precursor; acetyl-Coenzyme A acetyltransferase 1; acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase); EC 2.3.1.9; MAT; T2; THIL
Species Reactivity
Human, Mouse, Rat
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
ACAT1 antibody detects endogenous levels of total ACAT1 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
17,175 Da
OMIM
203750
3D Structure
ModBase 3D Structure for P24752
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human ACAT1.

Product Categories/Family for anti-ACAT1 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-ACAT1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ACAT1 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-ACAT1 antibody

Western blot analysis of extracts from A549 cells, 293 cells, Jurkat cells and HepG2 cells, using ACAT1 antibody.
Anti-ACAT1 Antibody – Cat# MBS857958

Product References and Citations for anti-ACAT1 antibody

Aboulaich N., Biochem. J. 383:237-248(2004). Fukao T., Hum. Mutat. 12:245-254(1998). Wakazono A., Hum. Mutat. 5:34-42(1995).

Other Notes

Small volumes of anti-ACAT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ACAT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
acetyl-CoA acetyltransferase, mitochondrial
NCBI Official Synonym Full Names
acetyl-CoA acetyltransferase 1
NCBI Official Symbol
ACAT1
NCBI Official Synonym Symbols
T2; MAT; ACAT; THIL
UniProt Protein Name
Acetyl-CoA acetyltransferase, mitochondrial
UniProt Synonym Protein Names
Acetoacetyl-CoA thiolase; T2
UniProt Gene Name
ACAT1
UniProt Synonym Gene Names
ACAT; MAT
NCBI Protein Information
acetyl-CoA acetyltransferase, mitochondrial

NCBI Summary for ACAT1

This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009]
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UniProt Comments for ACAT1

Plays a major role in ketone body metabolism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ACAT1 antibody

 Products by Pathway  Pathway Diagram
 Branched-chain Amino Acid Catabolism Pathway antibodies  Branched-chain Amino Acid Catabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies  C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
 C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies  C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Glyoxylate And Dicarboxylate Metabolism Pathway antibodies  Glyoxylate And Dicarboxylate Metabolism Pathway Diagram

Diseases associated with anti-ACAT1 antibody

 Disease Name  Pubmed Publications
 Atherosclerosis Antibodies  >64 publications with ACAT1 and Atherosclerosis
 Cardiovascular Diseases Antibodies  >46 publications with ACAT1 and Cardiovascular Diseases
 Hypercholesterolemia Antibodies  >16 publications with ACAT1 and Hypercholesterolemia
 Neoplasms Antibodies  >15 publications with ACAT1 and Neoplasms
 Dyslipidemias Antibodies  >15 publications with ACAT1 and Dyslipidemias
 Hyperlipidemias Antibodies  >14 publications with ACAT1 and Hyperlipidemias
 Nervous System Diseases Antibodies  >13 publications with ACAT1 and Nervous System Diseases
 Fatty Liver Antibodies  >11 publications with ACAT1 and Fatty Liver
 Liver Diseases Antibodies  >9 publications with ACAT1 and Liver Diseases
 Hypertension Antibodies  >8 publications with ACAT1 and Hypertension

Organs/Tissues associated with anti-ACAT1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >44 publications with ACAT1 and Blood
 Liver Antibodies  >40 publications with ACAT1 and Liver
 Intestine Antibodies  >18 publications with ACAT1 and Intestine
 Brain Antibodies  >9 publications with ACAT1 and Brain
 Muscle Antibodies  >8 publications with ACAT1 and Muscle
 Ovary Antibodies  >7 publications with ACAT1 and Ovary
 Bone Antibodies  >6 publications with ACAT1 and Bone
 Heart Antibodies  >5 publications with ACAT1 and Heart
 Kidney Antibodies  >5 publications with ACAT1 and Kidney
 Adipose Tissue Antibodies  >4 publications with ACAT1 and Adipose Tissue