Active Interferon Beta (IFNb)
Référence MBS2125333-0,1mg
Conditionnement : 0.1mg
Marque : MyBiosource
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SDS-PAGE
Interferon Beta (IFNb) Active Protein
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2125333SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
Interferon Beta (IFNb) is belongs to type I interferons (IFNs) family which a largesubgroup of interferon proteins that help regulate the activity of the immunesystem. The IFNb proteins are produced in large quantities by fibroblasts. Theyhave antiviral… More details
Product Overview
Online Datasheet in PDFProduct Name
Interferon Beta (IFNb), Active Protein
Full Product Name
Active Interferon Beta (IFNb)
Product Gene Name
IFNb active protein
Product Synonym Names
IFNb/Interferon Beta; IFNB1; IFN-B; IFB; IFF; IFNB; Interferon Beta 1 Fibroblast
Sequence
Met22~Asn1 87
Host
E Coli
Form/Format
Freeze-dried powder
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Purity/Purification
Greater than 97% by SDS-PAGE
Preparation and Storage
Store at 2-8 degree C for one month, -80 degree C for 12 months
Stable for 12 months if correctly stored.
The thermal stability is described by the loss rate. The loss rate was determinedby accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and noobvious degradation and precipitation were observed. The loss rate is less than 5% within theexpiration date under appropriate storage condition.
Stable for 12 months if correctly stored.
The thermal stability is described by the loss rate. The loss rate was determinedby accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and noobvious degradation and precipitation were observed. The loss rate is less than 5% within theexpiration date under appropriate storage condition.
Molecular Weight
22,294 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (21077104..21077943, complement). Location: 9p21
OMIM
147640
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Endotoxin
<1.0EU per 1ug (determined by the LAL method)
Tag
N-terminal His Tag
Biological Activity
Active
Expression System
Prokaryotic expression
Organism Species
Human
Isoelectric Point
8.9
Reconstitution
Reconstitute in 20mM Tris, 150mM NaCl (PH8.0) to a concentration of 0.1-1.0mg/mL. Do not vortex.
Product Categories/Family for IFNb active protein
Cytokine; Tumor immunity; Infection immunity; Active, prokaryotic recombinant
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for IFNb active protein
Cell culture, Activity Assays
Other Notes
Small volumes of IFNb active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for IFNb purchase
MBS2125333 is an active protein targeting IFNb. Also known as Active Interferon Beta (IFNb). Host: E Coli.
Additional Details
NCBI/Uniprot data below describe general gene information for IFNb. It may not necessarily be applicable to this product.
NCBI Official Full Name
interferon beta
NCBI Official Synonym Full Names
interferon, beta 1, fibroblast
NCBI Official Symbol
IFNB1
NCBI Official Synonym Symbols
IFB; IFF; IFNB
UniProt Protein Name
Interferon beta
UniProt Synonym Protein Names
Fibroblast interferon
Protein Family
Interferon
UniProt Gene Name
IFNB1
UniProt Synonym Gene Names
IFB; IFNB; IFN-beta
UniProt Entry Name
IFNB_HUMAN
NCBI Protein Information
interferon beta; IFN-beta; fibroblast interferon
UniProt Comments for IFNb
IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 9p21
Cellular Component: extracellular space; extracellular region
Molecular Function: interferon-alpha/beta receptor binding; cytokine activity
Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; response to virus; regulation of MHC class I biosynthetic process; natural killer cell activation; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; cell surface receptor linked signal transduction; response to exogenous dsRNA; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; positive regulation of innate immune response; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein; B cell activation during immune response
Show more Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 9p21
Cellular Component: extracellular space; extracellular region
Molecular Function: interferon-alpha/beta receptor binding; cytokine activity
Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; response to virus; regulation of MHC class I biosynthetic process; natural killer cell activation; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; cell surface receptor linked signal transduction; response to exogenous dsRNA; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; positive regulation of innate immune response; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein; B cell activation during immune response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with IFNb active protein
| Reference Product | PubMed Publications |
|---|---|
| IRF3 active protein | >12 publications with IFNb and IRF3 |
| IFNAR1 active protein | >4 publications with IFNb and IFNAR1 |
| IRF7 active protein | >3 publications with IFNb and IRF7 |
| STAT2 active protein | >2 publications with IFNb and STAT2 |
| IFNAR2 active protein | >1 publications with IFNb and IFNAR2 |
Pathways associated with IFNb active protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Chagas Disease (American Trypanosomiasis) Pathway antibodies | Chagas Disease (American Trypanosomiasis) Pathway Diagram |
| Chagas Disease (American Trypanosomiasis) Pathway antibodies | Chagas Disease (American Trypanosomiasis) Pathway Diagram |
| Cytokine Signaling In Immune System Pathway antibodies | Cytokine Signaling In Immune System Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokines And Inflammatory Response Pathway antibodies | Cytokines And Inflammatory Response Pathway Diagram |
| Cytosolic DNA-sensing Pathway antibodies | Cytosolic DNA-sensing Pathway Diagram |
| Cytosolic DNA-sensing Pathway antibodies | Cytosolic DNA-sensing Pathway Diagram |
| EBV LMP1 Signaling Pathway antibodies | EBV LMP1 Signaling Pathway Diagram |
| Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies | Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram |
Diseases associated with IFNb active protein
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >7 publications with IFNb and Neoplasms |
| Carcinoma Antibodies | >4 publications with IFNb and Carcinoma |
| Necrosis Antibodies | >4 publications with IFNb and Necrosis |
| Inflammation Antibodies | >3 publications with IFNb and Inflammation |
| Lung Neoplasms Antibodies | >2 publications with IFNb and Lung Neoplasms |
| Multiple Sclerosis Antibodies | >2 publications with IFNb and Multiple Sclerosis |
| Cardiovascular Diseases Antibodies | >2 publications with IFNb and Cardiovascular Diseases |
| Melanoma Antibodies | >2 publications with IFNb and Melanoma |
| Brain Diseases Antibodies | >2 publications with IFNb and Brain Diseases |
| Neoplasm Metastasis Antibodies | >1 publications with IFNb and Neoplasm Metastasis |