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> Alpha-synuclein Protein, Rat, Recombinant (GST)

Alpha-synuclein Protein, Rat, Recombinant (GST)

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Référence NB-64-51907-100ug

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Alpha-synuclein Protein, Rat, Recombinant (GST)

(Synonyms: Snca, Alpha-synuclein) Copy Product Info

Synonyms: Snca, Alpha-synuclein

Catalog No. TMPH-03238 Copy Product Info
Alpha-synuclein Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 41.5 kDa and the accession number is P37377.
Other Forms of Alpha-synuclein Protein, Rat, Recombinant (GST):
Alpha-synuclein Protein, Cynomolgus, Recombinant (His)
Alpha-synuclein Protein, Cynomolgus, Recombinant (His & SUMO)
Alpha-synuclein Protein, Pig, Recombinant (His & Myc)
Alpha-Synuclein Protein,Human,Recombinant (H50Q)
Alpha-Synuclein Protein, Mouse, Recombinant (His)
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Alpha-synuclein Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 41.5 kDa and the accession number is P37377.
Species
Rat
Expression System
E. coli
TagN-GST
Accession NumberP37377
Amino AcidMDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDQMGKGEEGYPQEGILEDMPVDPSSEAYEMPSEEGYQDYEPEA
Construction1-140 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsSnca, Alpha-synuclein
Research Background
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.
Chemical Properties
Molecular Weight41.5 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

α-synucleinαsynucleina-synuclein
Related Tags: Alpha-synuclein Protein, Rat, Recombinant (GST) chemical structure | Alpha-synuclein Protein, Rat, Recombinant (GST) molecular weight