Alvetex® Scaffold 12 Well Insert
AVP005-12 / AVP005-48 / AVP005-96
Brand: Alvetex®
The Alvetex 12 Well Insert enables long term 3D culture. Cells can receive media nutrients from above and below the membrane. Comprised of an Alvetex well insert containing Alvetex Scaffold (the insert is designed to hang in a well of a 6 well plate or a 12 well plate).
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Product Information
The Alvetex 12 Well Insert enables long term 3D culture. Cells can receive media nutrients from above and below the membrane.
Comprised of discs of Alvetex Scaffold in individually sealed polystyrene inserts, designed to fit into most 6 well and 12 well plates (see diagram).
Note: multiwell plate not included.
(For Alvetex Strata see Alvetex Strata 12 well inserts, STP012.)
12 well inserts (when their extender wings haven’t been snapped off) can also be suspended in a deep Petri dish using our custom-made Alvetex Well Insert Holder (see product AVP015, sold separately).
The presentation of Alvetex in well insert formats is versatile, enabling long term 3D culture as cells can receive nutrients from media above and below the membrane, sustaining optimal 3D cell growth.
About Alvetex
- Alvetex is a highly porous polystyrene scaffold designed for 3D cell culture
Cells grown in Alvetex possess a natural tissue-like structure that enables them to function in a more physiologically relevant manner. Alvetex 3D cell culture enables cells maintain their in vivo morphology, behavior and responsiveness within an in vitro model system. - Alvetex is a unique cellular environment
Manufactured to the highest standards of consistency each disc is engineered to a thickness of just 200 µm with pore sizes of 36-40 µm (Alvetex Scaffold). No cell is ever further than 100 µm from the nutrient source enabling easily exchange of nutrients, gases and waste products by passive diffusion across short distances. -
Maintain natural cell shape and morphology
In conventional 2D cell culture, cells come into contact with the flat surface of the culture vessel (e.g. Petri dish, flask or multi-well plate). In this unnatural environment cells become flattened against the substrate. In this abnormally thin structure there has been significant re-modelling of the internal cellular components. The entire cytoskeleton is remodeled and organelles such as the nucleus are flattened. -
Alvetex has been designed for simple and routine use
It uses conventional cell culture plasticware. Therefore any cell biologist can get into Alvetex 3D cell culture.- No specialist equipment is required
- No changes to media and optimized cell feeding protocols
- Compatible with the majority of down stream analytical techniques.
Say goodbye to risks of foreign unknown materials such as proteins or cytokines of animal origin — unlike conventional materials used in cell culture Alvetex is made from polystyrene and is completely inert.
▶ Find out more about the science of Alvetex
Available in varying formats and sizes.