ANP32A Antibody - middle region - Biotin
Référence ARP40203_P050-Biotin
Conditionnement : 100ul
Marque : Aviva Systems Biology
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ANP32A Antibody - middle region : Biotin (ARP40203_P050-Biotin)
| Datasheets/Manuals | Printable datasheet for anti-ANP32A (ARP40203_P050-Biotin) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | Biotin |
| Application | IHC, WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human ANP32A |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Sheep: 86%; Zebrafish: 86% |
| Peptide Sequence | Synthetic peptide located within the following region: FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDE |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-ANP32A (ARP40203_P050-Biotin) antibody is Catalog # AAP40203 (Previous Catalog # AAPS01612) |
| Sample Type Confirmation | ANP32A is supported by BioGPS gene expression data to be expressed in Jurkat |
| Reference | Stelzl,U., (2005) Cell 122 (6), 957-968 |
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| Gene Symbol | ANP32A |
| Gene Full Name | Acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| Alias Symbols | LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1 |
| NCBI Gene Id | 8125 |
| Protein Name | Acidic leucine-rich nuclear phosphoprotein 32 family member A |
| Description of Target | ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity. |
| Uniprot ID | P39687 |
| Protein Accession # | NP_006296 |
| Nucleotide Accession # | NM_006305 |
| Protein Size (# AA) | 249 |
| Molecular Weight | 29kDa |
| Protein Interactions | UBC; rev; PDLIM5; PLIN3; ARPC1B; OXSR1; EIF4A3; VBP1; TPD52L2; SSB; SRP14; RPA2; PKM; BAG1; SOX2; PCBP1; ESR1; THRB; PPARG; PGR; KPNA6; KPNA5; KPNA1; SUMO2; CHAF1A; HIST1H4A; HIST1H3A; HIST2H2BE; HIST2H2AC; SET; MEPCE; ELAVL1; ADAP1; NSFL1C; HSPB3; AXIN1; |
