Mouse anti-Human/Mouse CD28 Antibody
Anti-CD28 Antibody
Anti-CD28 Antibody
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Product Description
Specifications
| Size | 20 µg, 100 µg |
| Species | Human, Mouse |
| Host Species | Mouse |
| Accession Number | P10747 |
| Gene Id | 940 |
| Gene Symbols | CD28 |
| Protein Name / Synonyms | T-cell-specific surface glycoprotein CD28 (TP44) (CD antigen CD28) |
| Immunogen | Stimulated human leukocytes were used as the immunogen for the CD28 antibody. |
| Isotype | Kappa, IgG2a |
| Purity | Protein G affinity chromatography |
| Concentration (lot specific) | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Recommended Applications | Flow Cytometry: 0.5-1ug/million cells in 0.1ml Immunofluorescence: 0.5-1ug/ml Functional Activity (Order SAF formulation) |
| Domain / Region / Terminus | Cell surface |
| Research Area | Inflammation, Adaptive Immunity |
| Shipping Type | Blue ice |
| Storage | ≤-20°C |
Description
Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
Storage
Store the CD28 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Expiration:
12 months from the date of shipment when stored properly.