Anti-CD39 Antibody (8G885)
Référence NB-64-116053-50uL
Conditionnement : 50uL
Marque : Neo Biotech
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Anti-CD39 Antibody (8G885)
(Synonyms: SPG64, NTPDase-1, ectonucleoside triphosphate diphosphohydrolase 1, CD39, ATPDase) Copy Product InfoSynonyms: SPG64, NTPDase-1, ectonucleoside triphosphate diphosphohydrolase 1, CD39, ATPDase
Catalog No. TMAC-00704 Copy Product Info
Anti-CD39 Antibody (8G885) is a Rabbit antibody targeting CD39. Anti-CD39 Antibody (8G885) can be used in IHC,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Information
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CD39 Antibody (8G885) is a Rabbit antibody targeting CD39. Anti-CD39 Antibody (8G885) can be used in IHC,WB. |
| Synonyms | SPG64, NTPDase-1, ectonucleoside triphosphate diphosphohydrolase 1, CD39, ATPDase |
| Ig Type | IgG |
| Clone | 8G885 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of CD39 on different cell lysate using anti-CD39 antibody at 1/1,000 dilution. Positive control: Lane1: Human spleen, Lane2: Mouse placenta, Lane3: Mouse spleen. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD39 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD39 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-CD39 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse uterus tissue using anti-CD39 antibody. Counter stained with hematoxylin.  , , , , |
| Application | IHC WB |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. Alternative splicing gives rise to three CD39 isoforms, vascular, placenta I and placenta II. The placenta I isoform differs at the amino terminus whereas the placenta II isoform is missing amino acids 300-510 at the C-terminus. CD39 is expressed in vascular tissues including placenta, lung, skeletal muscle and kidney, as well as endothelium, smooth muscle, cardiac cells, lymphocytes (such as activated B cells) activated NK cells, macrophages, dendridic cells and platelets. CD39 may be used as an thrombic agent for pre-treating patients at risk for coronary artery occlusion and thrombic stroke. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID | P49961 |
| Molecular Weight | Theoretical: 70 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Keywords
SPG-64SPG 64CD-39CD 39
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