Anti-CNTF antibody
Référence MBS177049-0,1mg-PE
Conditionnement : 0.1mg(PE)
Marque : MyBiosource
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Téléphone : +1 850 650 7790
Anti-CNTF Picoband antibody, MBS177049-1.JPG
IHC(P): Rat Brain Tissue
IHC(P): Rat Brain Tissue
Anti-CNTF Picoband antibody, MBS177049-2.JPG
IHC(P): Human Intestinal Cancer Tissue
IHC(P): Human Intestinal Cancer Tissue
Anti-CNTF Picoband antibody, MBS177049-3.JPG
IHC(P): Human Lung Cancer Tissue
IHC(P): Human Lung Cancer Tissue
Anti-CNTF Picoband antibody, MBS177049-4.jpg
All lanes: Anti-CNTF(MBS177049) at 0.5ug/ml
WB: Recombinant Human CNTF Protein 0.5ng
Predicted bind size: 28KD
Observed bind size: 28KD
All lanes: Anti-CNTF(MBS177049) at 0.5ug/ml
WB: Recombinant Human CNTF Protein 0.5ng
Predicted bind size: 28KD
Observed bind size: 28KD
CNTF Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS177049Description: Rabbit IgG polyclonal antibody for Ciliary neurotrophic factor(CNTF) detection. Tested with WB, IHC-P in Human, Rat.Background: Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the… More details
Product Overview
Online Datasheet in PDFProduct Name
CNTF, Polyclonal Antibody
Full Product Name
Anti-CNTF antibody
Product Gene Name
anti-CNTF antibody
Product Synonym Names
Ciliary neurotrophic factor; ciliary neurotrophic factor; Ciliary Neurotrophic Factor antibody; CNTF antibody; CNTF_HUMAN antibody; HCNTF antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
Lyophilized
Purity/Purification
Immunogen affinity purified.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Molecular Weight
22,931 Da
OMIM
118945
Immunogen
E Coli-derived human CNTF recombinant protein (Position: A2-M200). Human CNTF shares 83% and 84% amino acid (aa) sequence identity with mouse and rat CNTF, respectively.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-CNTF antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Other Notes
Small volumes of anti-CNTF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for CNTF purchase
MBS177049 is an antibody targeting CNTF. Reactive in Human, Rat. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for CNTF. It may not necessarily be applicable to this product.
NCBI Official Full Name
Ciliary neurotrophic factor
NCBI Official Synonym Full Names
ciliary neurotrophic factor
NCBI Official Symbol
CNTF
NCBI Official Synonym Symbols
HCNTF
UniProt Protein Name
Ciliary neurotrophic factor
Protein Family
Ciliary neurotrophic factor
UniProt Gene Name
CNTF
UniProt Synonym Gene Names
CNTF
UniProt Entry Name
CNTF_HUMAN
NCBI Protein Information
ciliary neurotrophic factor
NCBI Summary for CNTF
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]
Show more UniProt Comments for CNTF
CNTF: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. Belongs to the CNTF family.
Chromosomal Location of Human Ortholog: 11q12.2
Cellular Component: extracellular space; cytoplasm
Molecular Function: interleukin-6 receptor binding; growth factor activity; ciliary neurotrophic factor receptor binding
Biological Process: negative regulation of photoreceptor cell differentiation; positive regulation of cell proliferation; regulation of retinal cell programmed cell death; neuron development; negative regulation of neuron apoptosis; signal transduction; muscle morphogenesis; growth; positive regulation of tyrosine phosphorylation of Stat3 protein
Show more Chromosomal Location of Human Ortholog: 11q12.2
Cellular Component: extracellular space; cytoplasm
Molecular Function: interleukin-6 receptor binding; growth factor activity; ciliary neurotrophic factor receptor binding
Biological Process: negative regulation of photoreceptor cell differentiation; positive regulation of cell proliferation; regulation of retinal cell programmed cell death; neuron development; negative regulation of neuron apoptosis; signal transduction; muscle morphogenesis; growth; positive regulation of tyrosine phosphorylation of Stat3 protein
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-CNTF antibody
| Reference Product | PubMed Publications |
|---|---|
| STAT3 antibody | >209 publications with CNTF and STAT3 |
| LIFR antibody | >129 publications with CNTF and LIFR |
| GFAP antibody | >114 publications with CNTF and GFAP |
| IL6ST antibody | >112 publications with CNTF and IL6ST |
| CNTFR antibody | >111 publications with CNTF and CNTFR |
| EGF antibody | >54 publications with CNTF and EGF |
| GAP43 antibody | >8 publications with CNTF and GAP43 |
| APOE antibody | >4 publications with CNTF and APOE |
| IL6R antibody | >1 publications with CNTF and IL6R |
Pathways associated with anti-CNTF antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Delta-Notch Signaling Pathway antibodies | Delta-Notch Signaling Pathway Diagram |
| Jak-STAT Signaling Pathway antibodies | Jak-STAT Signaling Pathway Diagram |
| Jak-STAT Signaling Pathway antibodies | Jak-STAT Signaling Pathway Diagram |
Diseases associated with anti-CNTF antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >594 publications with CNTF and Nervous System Diseases |
| Death Antibodies | >380 publications with CNTF and Death |
| Brain Diseases Antibodies | >300 publications with CNTF and Brain Diseases |
| Disease Models, Animal Antibodies | >241 publications with CNTF and Disease Models, Animal |
| Nerve Degeneration Antibodies | >196 publications with CNTF and Nerve Degeneration |
| Inflammation Antibodies | >110 publications with CNTF and Inflammation |
| Necrosis Antibodies | >91 publications with CNTF and Necrosis |
| Weight Loss Antibodies | >73 publications with CNTF and Weight Loss |
| Atrophy Antibodies | >69 publications with CNTF and Atrophy |
| Movement Disorders Antibodies | >58 publications with CNTF and Movement Disorders |
Organs/Tissues associated with anti-CNTF antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Nerve Antibodies | >1822 publications with CNTF and Nerve |
| Brain Antibodies | >1290 publications with CNTF and Brain |
| Eye Antibodies | >391 publications with CNTF and Eye |
| Embryonic Tissue Antibodies | >333 publications with CNTF and Embryonic Tissue |
| Ganglia Antibodies | >327 publications with CNTF and Ganglia |
| Muscle Antibodies | >326 publications with CNTF and Muscle |
| Spinal Cord Antibodies | >280 publications with CNTF and Spinal Cord |
| Blood Antibodies | >204 publications with CNTF and Blood |
| Bone Antibodies | >107 publications with CNTF and Bone |
| Vascular Antibodies | >78 publications with CNTF and Vascular |