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> Anti-dNK Polyclonal Antibody

Anti-dNK Polyclonal Antibody

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Référence OAAI00510

Conditionnement : 100ug

Marque : Aviva Systems Biology

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Anti-dNK Polyclonal Antibody (OAAI00510)

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fruit fly
Datasheets/ManualsPrintable datasheet for Anti-dNK Polyclonal Antibody (OAAI00510)
Product Info
Predicted Species ReactivityFruit fly
Product FormatLiquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
ClonalityPolyclonal
IsotypeRabbit IgG
HostRabbit
ApplicationELISA, FC, IHC, IP, WB
Additional InformationBackground: Deoxynucleoside kinases (dNK) are key enzymes in deoxyribonucleoside salvage, activating several clinically important chemotherapeutic drugs. Deoxynulceoside kinases catalyze the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribocytidine kinase (dCK), deoxyriboguanosine kinase(dGK), cytosolic thymidine kinase(TK1) and mitochondrial thymidine kinase (TK2).
::Positive Control: Fruit-fly extract
Reconstitution and StorageThe antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
ImmunogenA synthetic peptide corresponding to the N-terminus of fruit fly Deoxynucleoside kinase protein.
PurificationAffinity Purified
Concentration100ug/200ul
FormulationThis affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Application InfoWB: 0.1-1 ug/ml | ELISA: 0.01-0.1 ug/ml | IP: 2-5 ug/ml | IHC: 2-10 ug/ml | FC: Not tested
ReferenceHoskins,R.A., et al. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Science 316 (5831), 1625-1628 (2007) Sraffan Eriksson et al., Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy. Advances in Enzyme Regulation 34, pp13-25 (1994).
Gene Symboldnk
Gene Full Namedeoxyribonucleoside kinase
Alias SymbolsDNK, 2'-deoxynucleoside kinase, DM-dNK
Description of TargetDeoxynucleoside kinases (dNK) are key enzymes in deoxyribonucleoside salvage, activating several clinically important chemotherapeutic drμgs. Deoxynulceoside kinases catalyze the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribocytidine kinase (dCK), deoxyriboguanosine kinase(dGK), cytosolic thymidine kinase(TK1) and mitochondrial thymidine kinase (TK2).
Molecular Weight30