DNMT3A pAb
Anti-DNMT3A Antibody
Anti-DNMT3A Antibody
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Product Description
Specifications
| Size | 20 µL, 100 µL |
| Species | Human, Mouse, Rat |
| Host Species | Rabbit |
| Accession Number | Q9Y6K1 |
| Gene Id | 1788 |
| Gene Symbols | DNMT3A |
| Protein Name / Synonyms | DNMT3A, DNMT3A2, M.HsaIIIA, TBRS, DNA methyltransferase 3 alpha |
| Isotype | IgG |
| Purity | Affinity purification |
| Buffers | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Recommended Applications | Western Blotting, IHC, IF |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Dilutions
WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200
Format
Calculated MW
16kDa/81kDa/101kDa
Observed MW
95kDa
Immunogen
Recombinant protein of human DNMT3A
Modification
Unmodified
Storage
Store at -20°. Avoid freeze / thaw cycles.
Images
Expiration:
12 months from the date of shipment when stored properly.