Anti-DOPA Decarboxylase/DDC Antibody (1S353)
Référence NB-64-116523-100uL
Conditionnement : 100uL
Marque : Neo Biotech
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Anti-DOPA Decarboxylase/DDC Antibody (1S353)
(Synonyms: dopa decarboxylase (aromatic L-amino acid decarboxylase), Aadc) Copy Product InfoSynonyms: dopa decarboxylase (aromatic L-amino acid decarboxylase), Aadc
Catalog No. TMAC-01174 Copy Product Info
Anti-DOPA Decarboxylase/DDC Antibody (1S353) is a Rabbit antibody targeting DOPA Decarboxylase/DDC. Anti-DOPA Decarboxylase/DDC Antibody (1S353) can be used in IHC,WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-DOPA Decarboxylase/DDC Antibody (1S353) is a Rabbit antibody targeting DOPA Decarboxylase/DDC. Anti-DOPA Decarboxylase/DDC Antibody (1S353) can be used in IHC,WB. |
| Synonyms | dopa decarboxylase (aromatic L-amino acid decarboxylase), Aadc |
| Ig Type | IgG |
| Clone | 1S353 |
| Reactivity | Human,Mouse,Rat |
| Application | IHC WB |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | DOPA decarboxylase (DDC), also designated aromatic-L-amino-acid decarboxylase (AADC) belongs to the group II decarboxylase family of proteins. DDC, which can form a homodimer, is an important protein in the catecholamine biosynthesis pathway. DDC acts as a catalyst in the decarboxylation of L-5-hydroxytryptophan to serotonin, L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-tryptophan to tryptamine. Defects in the gene encoding for DDC may cause the autosomal recessive disorder AADC deficiency. AADC deficiency is an early onset inborn error in neurotransmitter metabolism which can lead to catecholamine and serotonin deficiency. This causes poor feeding, psychomotor and developmental delays, lethargy, ptosis, gastrointestinal disturbances and hypothermia. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID | P20711 |
| Molecular Weight | Theoretical: 53 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Keywords
dopa decarboxylasearomatic L-amino acid decarboxylase
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