Anti-Ficolin 1/FCN1 Antibody (7Q606)
Référence NB-64-122913-100uL
Conditionnement : 100uL
Marque : Neo Biotech
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Anti-Ficolin 1/FCN1 Antibody (7Q606)
(Synonyms: ficolin 1, FCNA, FCN1) Copy Product InfoSynonyms: ficolin 1, FCNA, FCN1
Catalog No. TMAY-01343 Copy Product Info
Anti-Ficolin 1/FCN1 Antibody (7Q606) is a Mouse antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (7Q606) can be used in ELISA(Det).
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-Ficolin 1/FCN1 Antibody (7Q606) is a Mouse antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (7Q606) can be used in ELISA(Det). |
| Synonyms | ficolin 1, FCNA, FCN1 |
| Ig Type | Mouse IgG1 |
| Clone | 7Q606 |
| Reactivity | Human |
| Specificity | Human ficolin 1/FCN1 No cross-reactivity in ELISA with Human cell lysate (293 cell line) |
| Application | ELISA(Det) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human FCN1 (rh FCN1; TMPY-01028; NP_001994.2; Met 1-Ala 326). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. Three Ficolins have been identified in humans: L-Ficolin, H-Ficolin and M-Ficolin (also referred to as Ficolin-2, -3 and -1, respectively). They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Dysfunction or abnormal expressions of Ficolins may involved in the pathogenesis of human diseases including infectious and inflammatory diseases, autoimmune disease and clinical syndrome of preeclampsia. They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Upon recognition of the infectious agent, the Ficolins act through two distinct routes: initiate the lectin pathway of complement activation through attached serine proteases (MASPs), and a primitive opsonophagocytosis thus limiting the infection and concurrently orchestrating the subsequent adaptive clonal immune response. Ficolin-1 (FCN1) is predominantly expressed in the peripheral blood leukocytes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human FCN1 protein (TMPY-01028) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Keywords
FCN-1FCN 1
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Related Tags: Anti-Ficolin 1/FCN1 Antibody (7Q606) chemical structure
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