Anti-HO-2 Antibody
Référence OAED00209
Conditionnement : 50ug
Marque : Aviva Systems Biology
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Anti-HO-2 Antibody (OAED00209)
| Datasheets/Manuals | Printable datasheet for Anti-HO-2 Antibody (OAED00209) |
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| Predicted Species Reactivity | Dog|Hamster|Human|Monkey|Mouse|Porcine|Rat |
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| Clonality | Polyclonal |
| Host | Rabbit |
| Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunoprecipitation|Western blot |
| Reconstitution and Storage | Long Term Storage : -20C |
| Immunogen | Synthetic peptide corresponding to the sequence near the N-terminus of human HO-2. |
| Purification | Protein A affinity purified. |
| Specificity | Recognizes human, mouse, rat, dog, hamster, monkey and pig HO-2. Detects a band of ~36kDa by Western blot. |
| Formulation | Liquid. In PBS containing 50% glycerol and 0.09% sodium azide. |
| Application Info | ELISA Immunocytochemistry Immunofluorescence Immunohistochemistry (1:50) Immunoprecipitation (10μg/ml, denatured) Western Blot (1:1000, colorimetric) Optimal conditions must be determined individually for each application. |
| Reference | Effects of hypoxia on heme oxygenase expression in human chorionic villi explants and immortalized trophoblast cells: G.E. Lash, et al. ; Am. J. Physiol. Heart Circ. Physiol. 284, H853 (2003), Application(s): WB using human samples, Abstract; Endogenous heme oxygenase prevents impairment of cerebral vascular functions caused by seizures: H. Parfenova, et al. ; Am. J. Physiol. Heart Circ. Physiol. 285, H1148 (2003), Application(s): WB using porcine samples, Abstract; Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene: V.J. Dzau, et al. ; Circulation 105, 602 (2002), Application(s): WB using rat samples, Abstract; Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants: M.P. Soares, et al. ; J. Immunol. 166, 4185 (2001), Application(s): WB using mouse samples, Abstract; Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimers disease: S.H. Snyder, et al. ; Neuron 28, 461 (2000), Application(s): ICC using rat samples, Abstract; |
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| Gene Symbol | HMOX2 |
| Gene Full Name | heme oxygenase 2 |
| Alias Symbols | heme oxygenase (decycling) 2;heme oxygenase 2;HO-2. |
| NCBI Gene Id | 3163 |
| Protein Name | Heme oxygenase 2 |
| Description of Target | Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter. |
| Uniprot ID | P30519 |
