Rat Anti-Mouse beta-Glucan Receptor [+FITC]
Anti-Mouse beta-Glucan Receptor Antibody, FITC
Anti-Mouse beta-Glucan Receptor Antibody, FITC
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Product Description
Specifications
| Size | 50 µg |
| Species | Mouse |
| Specificity | This product recognizes murine beta-glucan receptor, also known as Dectin-1.Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk. |
| Protein Name / Synonyms | beta-Glucan Receptor |
| Concentration (lot specific) | IgG concentration 0.1 mg/ml |
| Recommended Applications | Flow Cytometry |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline
Preparation
Immunogen:
Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1
Preservative:
| 0.09% | Sodium Azide |
| 1% | Bovine Serum Albumin |
This product
Spleen cells from immunised Fischer rats were fused with cells of the rat Y3 myeloma cell line
Expiration:
12 months from the date of shipment when stored properly.