Anti-TBXT Polyclonal Antibody
Référence NB-64-163336-100uL
Conditionnement : 100uL
Marque : Neo Biotech
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Anti-TBXT Polyclonal Antibody
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Catalog No. TMAB-13417 Copy Product Info
Anti-TBXT Polyclonal Antibody is a Rabbit antibody targeting TBXT. Anti-TBXT Polyclonal Antibody can be used in WB.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Information
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TBXT Polyclonal Antibody is a Rabbit antibody targeting TBXT. Anti-TBXT Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human) |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with Brachyury polyclonal antibody, unconjugated (TMAB-13417) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. [provided by RefSeq, Sep 2018] |
| Immunogen | KLH conjugated synthetic peptide: human Brachyury |
| Antigen Species | Human |
| Gene Name | TBXT |
| Gene ID | 6862 |
| Protein Name | T-box transcription factor T |
| Uniprot ID | O15178 |
| Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. |
| Molecular Weight | Theoretical: 48 kDa. Actual: 55 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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