General Information
| Short Description | Mouse monoclonal anti-Thyroid Hormone Receptor alpha 2 (N-Term) for use in WB in Human, Rat, Bovine, Mouse and Non-Human Primates samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human/Rat/Bovine/Mouse/Non-Human Primates |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1330 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | This antibody was protein g purified culture from supernatant. |
| Dilution Range | WB 1:1000 |
| Formulation | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Immunogen | Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH. |
| Immunogen Region | N-Term |
Additional Info
| Function | Isoform Alpha-1: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. Isoform Alpha-2: Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action. |
| Protein Name | Thyroid Hormone Receptor AlphaNuclear Receptor Subfamily 1 Group A Member 1V-Erba-Related Protein 7Ear-7C-Erba-1C-Erba-Alpha |
| Database Links | |
| Cellular Localisation | NucleusIsoform Alpha-2: CytoplasmWhen Overexpressed Found In The Cytoplasm Where It Colocalizes With Tacc1 |
| Alternative Antibody Names | Anti-Thyroid Hormone Receptor Alpha antibodyAnti-Nuclear Receptor Subfamily 1 Group A Member 1 antibodyAnti-V-Erba-Related Protein 7 antibodyAnti-Ear-7 antibodyAnti-C-Erba-1 antibodyAnti-C-Erba-Alpha antibodyAnti-THRA antibodyAnti-EAR7 antibodyAnti-ERBA1 antibodyAnti-NR1A1 antibodyAnti-THRA1 antibodyAnti-THRA2 antibody |
Information sourced from Uniprot.org