APC-Linked Monoclonal Antibody to Cytokeratin 19 (CK19)
Référence MBS2148138-0,2mL
Conditionnement : 0.2mL
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Cytokeratin 19 (CK19) Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2148138SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2148138 is an antibody targeting CK19. Also known as APC-Linked Monoclonal Antibody to Cytokeratin 19 (CK19). Reactive in Human, Pig. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
Cytokeratin 19 (CK19), Monoclonal Antibody
Full Product Name
APC-Linked Monoclonal Antibody to Cytokeratin 19 (CK19)
Product Gene Name
anti-CK19 antibody
Product Synonym Names
Cytokeratin 19; K19; KRT19; K1CS; Keratin 19; 40-kDa Keratin Intermediate Filament; Keratin, type I cytoskeletal 19
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
C7
Host
Mouse
Species Reactivity
Human, Pig
Form/Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Protein A + Protein G affinity chromatography
Concentration
>=0.1mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.
Stable for 12 months if correctly stored.
Matching Pairs
Unconjugated Antibody: CK19 Clone #C7 (MBS2152870)
APC Conjugated Antibody: CK19 Clone #C7 (MBS2148138)
APC Conjugated Antibody: CK19 Clone #C7 (MBS2148138)
Molecular Weight
44,106 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (39679869..39684641, complement). Location: 17q21.2
OMIM
148020
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
APC
Product Categories/Family for anti-CK19 antibody
Monoclonal Antibodies (Primary Abs); Primary, APC-conjugated; Tumor immunity
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CK19 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-CK19 antibody
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL
Other Notes
Small volumes of anti-CK19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CK19. It may not necessarily be applicable to this product.
NCBI Official Full Name
keratin, type I cytoskeletal 19
NCBI Official Synonym Full Names
keratin 19
NCBI Official Symbol
KRT19
NCBI Official Synonym Symbols
K19; CK19; K1CS
UniProt Protein Name
Keratin, type I cytoskeletal 19
UniProt Synonym Protein Names
Cytokeratin-19; CK-19; Keratin-19
UniProt Gene Name
KRT19
UniProt Synonym Gene Names
CK-19; K19
UniProt Entry Name
K1C19_HUMAN
NCBI Protein Information
keratin, type I cytoskeletal 19; CK-19; keratin-19; cytokeratin 19; cytokeratin-19; keratin, type I, 40-kd; 40-kDa keratin intermediate filament
NCBI Summary for CK19
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for CK19
K19: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 19 differs from all other IF proteins in lacking the C-terminal tail domain. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component: dystrophin-associated glycoprotein complex; costamere; intermediate filament; Z disc; sarcolemma
Molecular Function: protein binding; structural constituent of cytoskeleton; structural constituent of muscle; protein complex binding
Biological Process: viral reproduction; response to estrogen stimulus; sarcomere organization
Show more Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component: dystrophin-associated glycoprotein complex; costamere; intermediate filament; Z disc; sarcolemma
Molecular Function: protein binding; structural constituent of cytoskeleton; structural constituent of muscle; protein complex binding
Biological Process: viral reproduction; response to estrogen stimulus; sarcomere organization
Research Articles on CK19
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-CK19 antibody
| Reference Product | PubMed Publications |
|---|---|
| KRT15 antibody | >3 publications with CK19 and KRT15 |
| KRT6B antibody | >1 publications with CK19 and KRT6B |
| FANCG antibody | >1 publications with CK19 and FANCG |
Pathways associated with anti-CK19 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Signaling Mediated By P38-alpha And P38-beta Pathway antibodies | Signaling Mediated By P38-alpha And P38-beta Pathway Diagram |
Diseases associated with anti-CK19 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >42 publications with CK19 and Neoplasms |
| Carcinoma Antibodies | >25 publications with CK19 and Carcinoma |
| Adenocarcinoma Antibodies | >13 publications with CK19 and Adenocarcinoma |
| Breast Neoplasms Antibodies | >9 publications with CK19 and Breast Neoplasms |
| Liver Diseases Antibodies | >8 publications with CK19 and Liver Diseases |
| Neoplasm Metastasis Antibodies | >7 publications with CK19 and Neoplasm Metastasis |
| Liver Neoplasms Antibodies | >5 publications with CK19 and Liver Neoplasms |
| Carcinoma, Hepatocellular Antibodies | >5 publications with CK19 and Carcinoma, Hepatocellular |
| Kidney Diseases Antibodies | >4 publications with CK19 and Kidney Diseases |
| Fibrosis Antibodies | >4 publications with CK19 and Fibrosis |
Organs/Tissues associated with anti-CK19 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Liver Antibodies | >12 publications with CK19 and Liver |
| Blood Antibodies | >12 publications with CK19 and Blood |
| Lung Antibodies | >6 publications with CK19 and Lung |
| Bone Antibodies | >5 publications with CK19 and Bone |
| Kidney Antibodies | >4 publications with CK19 and Kidney |
| Thyroid Antibodies | >4 publications with CK19 and Thyroid |
| Eye Antibodies | >3 publications with CK19 and Eye |
| Stomach Antibodies | >3 publications with CK19 and Stomach |
| Pancreas Antibodies | >3 publications with CK19 and Pancreas |
| Lymph Antibodies | >2 publications with CK19 and Lymph |