APC-Linked Polyclonal Antibody to Caspase 3 (CASP3)
Référence MBS2146883-0,2mL
Conditionnement : 0.2mL
Marque : MyBiosource
Caspase 3 (CASP3) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2146883SPECIAL PROMOTION: Get FREE Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment
MBS2146883 is an antibody targeting CASP3. Also known as APC-Linked Polyclonal Antibody to Caspase 3 (CASP3). Reactive in Bovine. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Caspase 3 (CASP3), Polyclonal Antibody
Full Product Name
APC-Linked Polyclonal Antibody to Caspase 3 (CASP3)
Product Gene Name
anti-CASP3 antibody
Product Synonym Names
Caspase 3; CPP32; CPP32B; SCA1; Apoptain; Yama; Apoptosis-Related Cysteine Peptidase; Cysteinyl Aspartate Specific Proteinases 3; SREBP cleavage activity 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Bovine
Form/Format
Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Purity/Purification
Affinity Chromatography
Concentration
>=0.1mg/mL (Please refer to the vial label for the specific concentration.) (lot specific)
Preparation and Storage
Store at 2 degree C to 8 degree C for frequent use, -20 degree C for 12 months
Stable for 12 months if correctly stored.
Stable for 12 months if correctly stored.
Matching Pairs
Antibody: CASP3 (MBS2146883)
Immunogen: CASP3 (MBS2105285)
Immunogen: CASP3 (MBS2105285)
Matching Pairs
Unconjugated Antibody: CASP3 (MBS2151622)
APC Conjugated Antibody: CASP3 (MBS2146883)
APC Conjugated Antibody: CASP3 (MBS2146883)
Molecular Weight
31,136 Da
Immunogen Sequence Positions
Ser29~Asp175
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Conjugation
APC
Product Categories/Family for anti-CASP3 antibody
Polyclonal Antibodies (Primary Abs); Primary, APC-conjugated; Signal transduction
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-CASP3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes for anti-CASP3 antibody
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL
Other Notes
Small volumes of anti-CASP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CASP3. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
caspase-3
NCBI Official Symbol
CASP3
UniProt Protein Name
Caspase-3
Protein Family
Caspase
UniProt Gene Name
CASP3
UniProt Synonym Gene Names
CASP-3
NCBI Protein Information
caspase-3
UniProt Comments for CASP3
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage ().
Show more Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-CASP3 antibody
| Reference Product | PubMed Publications |
|---|---|
| CASP9 antibody | >7299 publications with CASP3 and CASP9 |
| CASP8 antibody | >5152 publications with CASP3 and CASP8 |
| XIAP antibody | >978 publications with CASP3 and XIAP |
| CASP6 antibody | >473 publications with CASP3 and CASP6 |
| APAF1 antibody | >348 publications with CASP3 and APAF1 |
| CASP2 antibody | >57 publications with CASP3 and CASP2 |
| BIRC3 antibody | >47 publications with CASP3 and BIRC3 |
| PAK2 antibody | >31 publications with CASP3 and PAK2 |
| CDH1 antibody | >10 publications with CASP3 and CDH1 |
| DFFA antibody | >5 publications with CASP3 and DFFA |
Diseases associated with anti-CASP3 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Necrosis Antibodies | >6413 publications with CASP3 and Necrosis |
| Nervous System Diseases Antibodies | >5034 publications with CASP3 and Nervous System Diseases |
| Inflammation Antibodies | >3501 publications with CASP3 and Inflammation |
| Reperfusion Injury Antibodies | >2247 publications with CASP3 and Reperfusion Injury |
| Liver Diseases Antibodies | >2195 publications with CASP3 and Liver Diseases |
| Brain Ischemia Antibodies | >1601 publications with CASP3 and Brain Ischemia |
| Heart Diseases Antibodies | >1502 publications with CASP3 and Heart Diseases |
| Breast Neoplasms Antibodies | >1401 publications with CASP3 and Breast Neoplasms |
| Neoplasms, Experimental Antibodies | >1259 publications with CASP3 and Neoplasms, Experimental |
| Kidney Diseases Antibodies | >853 publications with CASP3 and Kidney Diseases |
Organs/Tissues associated with anti-CASP3 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >7401 publications with CASP3 and Brain |
| Intestine Antibodies | >877 publications with CASP3 and Intestine |
| Pancreas Antibodies | >737 publications with CASP3 and Pancreas |
| Uterus Antibodies | >221 publications with CASP3 and Uterus |
| Pineal Gland Antibodies | >38 publications with CASP3 and Pineal Gland |
| Uncharacterized Tissue Antibodies | >6 publications with CASP3 and Uncharacterized Tissue |
| Rumen Antibodies | >4 publications with CASP3 and Rumen |


