Aromatase inhibitor 23 [32585-54-9]
Référence T60006-5mg
Conditionnement : 5mg
Marque : TargetMol
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Aromatase inhibitor 23
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Aromatase inhibitor 23 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases.
Cas No. 32585-54-9
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.54%
Appearance:Solid
Color:White
COA LCMS HNMR
Product Information
Aromatase inhibitor 23 AI Summary
Aromatase inhibitor 23 exhibits a diverse range of bioactivities, including modulation of lipid storage in Drosophila S3 cells and identification as a potential general anesthetic through a competitive binding assay. It inhibits chronic active B-cell receptor signaling, ELG1-dependent DNA repair, the malarial parasite plastid, Polymerase Iota, TGF-β, Glutaminase (GLS), the HIV-1 protein Vpr, Vaccinia Orthopoxvirus, and the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). Additionally, it has been screened for antiviral properties against Foot and Mouth Disease Virus. The compound shows cytotoxicity against human MCF7 cells, evident from reduced cell metabolic activity in MTT assays after 24 and 48 hours, and releases LDH in these cells. Furthermore, Aromatase inhibitor 23 exhibits significant inhibition of recombinant human aromatase, with an IC50 value of 200.0 nM and an inhibition percentage of 109.7%. These findings highlight its potential applications in various biological processes and diseases..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Aromatase inhibitor 23 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases. |
| Molecular Weight | 300.38 |
| Formula | C16H16N2O2S |
| Cas No. | 32585-54-9 |
| Smiles | C(CNS(=O)(=O)C1=CC=CC=C1)C=2C=3C(NC2)=CC=CC3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (183.1 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||