bFGF Polyclonal Antibody Cy5 Conjugated
Référence MBS9459817-0,1mL
Conditionnement : 0.1mL
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bFGF Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9459817Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro (By similarity). More details
Product Overview
Online Datasheet in PDFProduct Name
bFGF, Polyclonal Antibody
Full Product Name
bFGF Polyclonal Antibody Cy5 Conjugated
Product Gene Name
anti-bFGF antibody
Product Synonym Names
Fgfb; bFGF; Fgf-2; Fibroblast growth factor 2; Basic fibroblast growth factor; Heparin-binding growth factor 2; HBGF-2; Fgf2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Rabbit, Guinea pig
Form/Format
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Purity/Purification
Purified by Protein A
Concentration
1mgml (lot specific)
Preparation and Storage
Store at 4 degree C for 12 months.
Applications Tested/Suitable for anti-bFGF antibody
Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Application Notes for anti-bFGF antibody
FC/FACS:1:20-10
IF: 1:50-200
IF: 1:50-200
Other Notes
Small volumes of anti-bFGF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for bFGF purchase
MBS9459817 is an antibody targeting bFGF. Also known as bFGF Polyclonal Antibody Cy5 Conjugated. Reactive in Human, Mouse, Rat, Rabbit, Guinea pig. Host: Rabbit.
Additional Details
NCBI/Uniprot data below describe general gene information for bFGF. It may not necessarily be applicable to this product.
NCBI Official Full Name
fibroblast growth factor 2
NCBI Official Synonym Full Names
fibroblast growth factor 2
NCBI Official Symbol
Fgf2
NCBI Official Synonym Symbols
Fgfb; bFGF; Fgf-2
UniProt Protein Name
Fibroblast growth factor 2
UniProt Synonym Protein Names
Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2
Protein Family
Fibroblast growth factor
UniProt Gene Name
Fgf2
UniProt Synonym Gene Names
Fgf-2; FGF-2; bFGF; HBGF-2
UniProt Entry Name
FGF2_MOUSE
NCBI Protein Information
fibroblast growth factor 2; HBGF-2; basic fibroblast growth factor; heparin-binding growth factor 2
UniProt Comments for bFGF
FGF2: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with CSPG4, FGFBP1 and TEC. Found in a complex with FGFBP1, FGF1 and FGF2. Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue. Belongs to the heparin-binding growth factors family. 4 isoforms of the human protein are produced by alternative initiation.
Protein type: Motility/polarity/chemotaxis; Activator
Cellular Component: extracellular space; cytoplasm; extracellular region; cytosol; nucleus
Molecular Function: heparin binding; protein binding; ligand-dependent nuclear receptor transcription coactivator activity; growth factor activity; cytokine activity; fibroblast growth factor receptor binding; chemoattractant activity; receptor binding
Biological Process: wound healing; activation of MAPKK activity; regulation of cell cycle; positive regulation of smooth muscle cell proliferation; positive regulation of transcription, DNA-dependent; multicellular organismal development; adrenocorticotropin hormone secreting cell differentiation; cardiac muscle cell proliferation; thyroid stimulating hormone secreting cell differentiation; hyaluronan catabolic process; growth factor dependent regulation of satellite cell proliferation; positive regulation of MAP kinase activity; embryonic development ending in birth or egg hatching; negative regulation of cell proliferation; glial cell differentiation; substantia nigra development; positive chemotaxis; induction of an organ; positive regulation of cell proliferation; regulation of retinal cell programmed cell death; angiogenesis; response to axon injury; cell differentiation; positive regulation of granule cell precursor proliferation; positive regulation of cardiac muscle cell proliferation; fibroblast growth factor receptor signaling pathway; positive regulation of cell fate specification; positive regulation of blood vessel endothelial cell migration; positive regulation of phosphoinositide 3-kinase activity; negative regulation of blood vessel endothelial cell migration; positive regulation of osteoblast differentiation; positive regulation of protein kinase B signaling cascade; stem cell development; positive regulation of angiogenesis; cell migration during sprouting angiogenesis; ureteric bud branching; release of sequestered calcium ion into cytosol; positive regulation of cell division; phosphatidylinositol biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of endothelial cell proliferation; positive regulation of protein amino acid phosphorylation; positive regulation of cell differentiation; positive regulation of epithelial cell proliferation; inositol phosphate biosynthetic process; lung development
Show more Protein type: Motility/polarity/chemotaxis; Activator
Cellular Component: extracellular space; cytoplasm; extracellular region; cytosol; nucleus
Molecular Function: heparin binding; protein binding; ligand-dependent nuclear receptor transcription coactivator activity; growth factor activity; cytokine activity; fibroblast growth factor receptor binding; chemoattractant activity; receptor binding
Biological Process: wound healing; activation of MAPKK activity; regulation of cell cycle; positive regulation of smooth muscle cell proliferation; positive regulation of transcription, DNA-dependent; multicellular organismal development; adrenocorticotropin hormone secreting cell differentiation; cardiac muscle cell proliferation; thyroid stimulating hormone secreting cell differentiation; hyaluronan catabolic process; growth factor dependent regulation of satellite cell proliferation; positive regulation of MAP kinase activity; embryonic development ending in birth or egg hatching; negative regulation of cell proliferation; glial cell differentiation; substantia nigra development; positive chemotaxis; induction of an organ; positive regulation of cell proliferation; regulation of retinal cell programmed cell death; angiogenesis; response to axon injury; cell differentiation; positive regulation of granule cell precursor proliferation; positive regulation of cardiac muscle cell proliferation; fibroblast growth factor receptor signaling pathway; positive regulation of cell fate specification; positive regulation of blood vessel endothelial cell migration; positive regulation of phosphoinositide 3-kinase activity; negative regulation of blood vessel endothelial cell migration; positive regulation of osteoblast differentiation; positive regulation of protein kinase B signaling cascade; stem cell development; positive regulation of angiogenesis; cell migration during sprouting angiogenesis; ureteric bud branching; release of sequestered calcium ion into cytosol; positive regulation of cell division; phosphatidylinositol biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; positive regulation of endothelial cell proliferation; positive regulation of protein amino acid phosphorylation; positive regulation of cell differentiation; positive regulation of epithelial cell proliferation; inositol phosphate biosynthetic process; lung development
Research Articles on bFGF
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-bFGF antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Activated Point Mutants Of FGFR2 Pathway antibodies | Activated Point Mutants Of FGFR2 Pathway Diagram |
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies | Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram |
| DAP12 Interactions Pathway antibodies | DAP12 Interactions Pathway Diagram |
| DAP12 Signaling Pathway antibodies | DAP12 Signaling Pathway Diagram |
| Disease Pathway antibodies | Disease Pathway Diagram |
| Downstream Signal Transduction Pathway antibodies | Downstream Signal Transduction Pathway Diagram |
| Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies | Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram |
| Downstream Signaling Of Activated FGFR Pathway antibodies | Downstream Signaling Of Activated FGFR Pathway Diagram |
| ESC Pluripotency Pathways antibodies | ESC Pluripotency Pathways Diagram |
Diseases associated with anti-bFGF antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >983 publications with bFGF and Nervous System Diseases |
| Necrosis Antibodies | >618 publications with bFGF and Necrosis |
| Wounds and Injuries Antibodies | >576 publications with bFGF and Wounds and Injuries |
| Inflammation Antibodies | >444 publications with bFGF and Inflammation |
| Heart Diseases Antibodies | >419 publications with bFGF and Heart Diseases |
| Myocardial Ischemia Antibodies | >347 publications with bFGF and Myocardial Ischemia |
| Disease Progression Antibodies | >340 publications with bFGF and Disease Progression |
| Lung Diseases Antibodies | >325 publications with bFGF and Lung Diseases |
| Hyperplasia Antibodies | >258 publications with bFGF and Hyperplasia |
| Lung Neoplasms Antibodies | >226 publications with bFGF and Lung Neoplasms |
Organs/Tissues associated with anti-bFGF antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >2179 publications with bFGF and Brain |
| Eye Antibodies | >1024 publications with bFGF and Eye |
| Stomach Antibodies | >126 publications with bFGF and Stomach |
| Inner Ear Antibodies | >71 publications with bFGF and Inner Ear |
| Mammary Gland Antibodies | >40 publications with bFGF and Mammary Gland |
| Extraembryonic Tissue Antibodies | >20 publications with bFGF and Extraembryonic Tissue |