ICH2254LALA-100mg | Bulk Human IgG1 (IB1) Isotype Control LALA Biovalley

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Bulk Human IgG1 (IB1) Isotype Control LALA

Endotoxin

<1.0 EU/mg as determined by the LAL method

Purity

≥95% monomer by analytical SEC, >95% by SDS Page

Species Reactivity

Target

Concentration

Isotype

Host

Aggregation

Buffer

Uniprot

Rrid

Shipping Conditions

Background

Clone IB1 is a human IgG1 isotype control bearing the LALA (L234A/L235A) Fc mutations that silence FcγR engagement, making it a precise negative control for studies where effector function must be removed. Featuring the same IgG1 framework as many therapeutic-style test antibodies, IB1 LALA defines background binding and gating boundaries in flow cytometry and functional assays without contributing specific antigen recognition. Anti-IgG1 control clone IB1 is offered in a low-endotoxin formulation suitable for in vivo use and produced in scalable milligram to gram quantities to serve bulk and high-throughput laboratories. It is a research-use-only, non-therapeutic reagent.

Other Names

Clone

Specificity

This Human IgG1 isotype control recombinant antibody has been tested against selected species' cells and tissues to assure minimal cross reactivity. Furthermore, this low endotoxin Human IgG1 antibody is suitable for in vivo applications and each lot is IMPACT I certified.

Purification Method

Fc Modification

Formulation

Storage

Applications

Application Notes

Use

Bio X Cell Code

Faq (q&a)

Q: Is clone IB1 suitable for in vivo use?

A: Yes - IB1 is supplied in a low-endotoxin, in vivo-grade format for use as a matched Human IgG1 negative control in in vivo and in vitro studies.

Q: Can I order the IB1 isotype control in bulk?

A: Yes, it is manufactured in scalable milligram to gram quantities to support high-throughput and bulk experiments.

Q: What is clone IB1 used for?

A: It is a non-targeting Human IgG1 antibody used as an isotype-matched negative control to assess background and Fc effects; for research use only (RUO).

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Bulk Human IgG1 (IB1) Isotype Control LALA

Référence ICH2254LALA-100mg

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Bulk Human IgG1 (IB1) Isotype Control LALA