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> Calmodulin (Phosphodiesterase 3'-5'-Cyclic Nucleotide Activator) (FITC)

Calmodulin (Phosphodiesterase 3'-5'-Cyclic Nucleotide Activator) (FITC)

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Référence C1035-05-FITC-100ul

Conditionnement : 100ul

Marque : US Biological

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C1035-05-FITCCalmodulin (Phosphodiesterase 3'-5'-Cyclic Nucleotide Activator) (FITC)

Specifications
Clone TypeMonoclonal
Hostmouse
Sourcebovine
Swiss ProtP62157
IsotypeIgG1
GradeAffinity Purified
ApplicationsIP RIA WB
CrossreactivityBo Hu Mo Po Rt
Accession #NP_008819
Shipping TempBlue Ice
Storage Temp-20°C

Calmodulin (CaM) is a ubiquitous, calcium-binding protein that can bind to and regulate a multitude of different protein targets, thereby affecting many different cellular functions.

Applications:
Suitable for use in Western Blot, Immunoprecipation and RIA. Other applications not tested.

Recommended Dilutions:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 

Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG1|Clone No: 0.T.172|Host: mouse|Source: bovine|Concentration: As Reported |Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).|Purity: Purified by Protein G affinity chromatography.|Immunogen: Synthetic peptide corresponding to the 21 C-terminal amino acids (aa128-148) of bovine calmodulin, conjugated with tyroglobulin|Specificity: Recognizes both Ca 2+-bound and Ca 2+-free bovine calmodulin. Does not recognize bovine S100-alpha, S100-beta, troponin C or parvalbumin. Species crossreactivity: rat, mouse, human, porcine and wheat germ. Wide crossreactivity expected.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Synthetic peptide corresponding to the 21 C-terminal amino acids (aa128-148) of bovine calmodulin, conjugated with tyroglobulin
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes both Ca 2+-bound and Ca 2+-free bovine calmodulin. Does not recognize bovine S100-alpha, S100-beta, troponin C or parvalbumin. Species crossreactivity: rat, mouse, human, porcine and wheat germ. Wide crossreactivity expected.
References
1. Xu, Jing, et al. (2007). Hippocampus. 17: 525- 37. 2. Liang, L., et al. (2000). J Biol Chem. 275: 30075-81. 3. Kapus, A., et al. (1999). J Biol Chem. 274: 8093-102. 4. Lee, A., et al. (1999). Nature. 399: 155-9. 5. Deisseroth, K., et al. (1998). Nature. 392: 198-202.