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> CD14 (PE/CY5)

CD14 (PE/CY5)

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Référence C2265-31D-100T

Conditionnement : 100Tests

Marque : US Biological

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C2265-31DCD14 (PE/CY5)

Specifications
Clone TypeMonoclonal
Hostmouse
Sourcehuman
IsotypeIgG1,k
GradePurified
ApplicationsFC
CrossreactivityCa Hu Mk
Shipping TempBlue Ice
Storage Temp4°C Do not freeze

CD14 is a 53-55kD glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilutions:
Flow Cytometry: Use 10ul to label 10e6 cells
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Caution: PE/CY5 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Applications
Product Type: Mab|Isotype: IgG1,k|Clone No: 5K63 (61D3)|Host: mouse|Source: human|Concentration: Not Determined|Form: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide and a stabilizing agent. Labeled with PE/CY5.|Purity: Purified|Immunogen: Human peripheral monocytes|Specificity: Recognizes human CD14. Species Crossreactivity: Cynomolgus monkey, canine and hooded seal||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Human peripheral monocytes
Form
Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide and a stabilizing agent. Labeled with PE/CY5.
Purity
Purified
Specificity
Recognizes human CD14. Species Crossreactivity: Cynomolgus monkey, canine and hooded seal
References
1. Knapp, W., B. Dorken, W.R. GIlks, E.P. Rieber, R.E. Schmidt, H. Stein, A.E.G.K. Von dem Borne, eds. 1989. Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, Oxford. 2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD14 Section, Academic Press, New York, p. 169. 3. Hogg, N., S. MacDonald, M. Slusarenko, and P.C. Beverley. 1984. Immunol. 53:753. 4. Stocks, S.C., M. Albrechtsen, and M.A. Kerr. 1990. Biochem. J. 268:275.