CD19 antibody (PE-Texas Red)

Référence MBS530659-5x100

Conditionnement : 5x100Pieces

Marque : MyBiosource

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CD19 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS530659

MBS530659 is an antibody targeting CD19. Also known as CD19 antibody (PE-Texas Red). Reactive in Human. Host: Mouse. Mouse monoclonal CD19 antibody (PE-Texas Red) More details

Product Overview

Online Datasheet in PDF
Product Name
CD19, Monoclonal Antibody
Full Product Name
CD19 antibody (PE-Texas Red)
Product Gene Name
anti-CD19 antibody
Product Synonym Names
Monoclonal CD19; Anti-CD19; CD 19; CD19; CD-19
Clonality
Monoclonal
Isotype
IgG1
Clone Number
SJ25-C1
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, with NaN3 added as preservative.
Concentration
0.1 mg/ml (lot specific)
Specificity
Human
Preparation and Storage
Store at 4 degree C.
Molecular Weight
61,200 Da
OMIM
107265
3D Structure
ModBase 3D Structure for P15391
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Tag/Conjugate
PE-Texas Red
Immunogen
CD19 antibody (PE-Texas Red) was raised in mouse using human CD19 as the immunogen.

Product Categories/Family for anti-CD19 antibody

Immunology; Conjugated Monoclonal Antibodies
Applications Tested/Suitable for anti-CD19 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)

Other Notes

Small volumes of anti-CD19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD19. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
B-lymphocyte antigen CD19 isoform 2
NCBI Official Synonym Full Names
CD19 molecule
NCBI Official Symbol
CD19
NCBI Official Synonym Symbols
B4; CVID3
UniProt Protein Name
B-lymphocyte antigen CD19
UniProt Synonym Protein Names
B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD_antigen: CD19
Protein Family
B-lymphocyte antigen
UniProt Gene Name
CD19
UniProt Entry Name
CD19_HUMAN
NCBI Protein Information
B-lymphocyte antigen CD19

NCBI Summary for CD19

Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD19

CD19: a cell surface molecule which assembles with the antigen receptor of B lymphocytes. A critical signal transduction molecule that regulates B lymphocyte development, activation, and differentiation. Ligation increases intracellular calcium levels and decreases the threshold for antigen receptor signaling. Germinal center formation is significantly reduced in CD19-deficient mice.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: protein complex; integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: receptor signaling protein activity

Biological Process: epidermal growth factor receptor signaling pathway; B cell receptor signaling pathway; regulation of immune response; cell surface receptor linked signal transduction; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; innate immune response; cellular defense response; positive regulation of release of sequestered calcium ion into cytosol

Disease: Immunodeficiency, Common Variable, 2; Immunodeficiency, Common Variable, 3
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CD19 antibody

 Reference Product  PubMed Publications
 CD22 antibody  >614 publications with CD19 and CD22
 CD79A antibody  >152 publications with CD19 and CD79A
 CD81 antibody  >102 publications with CD19 and CD81
 CR2 antibody  >76 publications with CD19 and CR2
 LYN antibody  >59 publications with CD19 and LYN
 SYK antibody  >49 publications with CD19 and SYK
 VAV1 antibody  >13 publications with CD19 and VAV1
 PIK3R1 antibody  >2 publications with CD19 and PIK3R1

Pathways associated with anti-CD19 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway antibodies  Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 Constitutive Signaling By Aberrant PI3K In Cancer Pathway antibodies  Constitutive Signaling By Aberrant PI3K In Cancer Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram

Diseases associated with anti-CD19 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >459 publications with CD19 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >433 publications with CD19 and Vascular Diseases
 Inflammation Antibodies  >378 publications with CD19 and Inflammation
 Necrosis Antibodies  >339 publications with CD19 and Necrosis
 Neoplasms, Experimental Antibodies  >326 publications with CD19 and Neoplasms, Experimental
 Death Antibodies  >274 publications with CD19 and Death
 Lung Diseases Antibodies  >217 publications with CD19 and Lung Diseases
 Liver Diseases Antibodies  >171 publications with CD19 and Liver Diseases
 Common Variable Immunodeficiency Antibodies  >93 publications with CD19 and Common Variable Immunodeficiency
 Agammaglobulinemia Antibodies  >89 publications with CD19 and Agammaglobulinemia

Organs/Tissues associated with anti-CD19 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6409 publications with CD19 and Blood
 Bone Marrow Antibodies  >1781 publications with CD19 and Bone Marrow
 Spleen Antibodies  >590 publications with CD19 and Spleen
 Lymph Node Antibodies  >483 publications with CD19 and Lymph Node
 Lymph Antibodies  >433 publications with CD19 and Lymph
 Lung Antibodies  >218 publications with CD19 and Lung
 Thymus Antibodies  >175 publications with CD19 and Thymus
 Brain Antibodies  >143 publications with CD19 and Brain
 Tonsil Antibodies  >119 publications with CD19 and Tonsil
 Intestine Antibodies  >107 publications with CD19 and Intestine