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> CD2 (T-cell Surface Antigen CD2, Erythrocyte Receptor, LFA-2, LFA-3 Receptor, Rosette Receptor, T-cell Surface Antigen T11/Leu-5, SRBC) (PerCP/Cy5.5)

CD2 (T-cell Surface Antigen CD2, Erythrocyte Receptor, LFA-2, LFA-3 Receptor, Rosette Receptor, T-cell Surface Antigen T11/Leu-5, SRBC) (PerCP/Cy5.5)

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Référence 367050-100T

Conditionnement : 100Tests

Marque : US Biological

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367050CD2 (T-cell Surface Antigen CD2, Erythrocyte Receptor, LFA-2, LFA-3 Receptor, Rosette Receptor, T-cell Surface Antigen T11/Leu-5, SRBC) (PerCP/Cy5.5)

Specifications
Clone TypeMonoclonal
Hostmouse
Sourcehuman
Swiss ProtP06730
IsotypeIgG1,k
GradeHighly Purified
ApplicationsFC
CrossreactivityHu
Accession #NM_001767.4
Shipping TempBlue Ice
Storage Temp4°C Do Not Freeze

CD2 is a 50kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is a specific marker for T lymphocytes, natural killer cells, thymic B cell subsets, and some antigen presenting cells. CD2 interacts with CD58 (LFA-3) and CD48 to mediate cell adhesion and induce co-stimulatory signals in T lymphocytes.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 5ul is sufficient for staining of 1 million cells in a 100ul staining volume or 100ul of whole blood
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. PerCP conjugates are sensitive to light.

Applications
Product Type: Mab|Isotype: IgG1,k|Clone No: OKT13|Host: mouse|Source: human|Concentration: ~0.1mg/ml|Form: Supplied as a liquid in PBS, pH 7.2, 0.2% BSA, 0.09% sodium azide. Labeled with PerCP/Cy5.5. |Purity: Highly Purified|Immunogen: Human acute lymphoblastic leukemia cells|Specificity: Recognizes human CD2. ||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Human acute lymphoblastic leukemia cells
Form
Supplied as a liquid in PBS, pH 7.2, 0.2% BSA, 0.09% sodium azide. Labeled with PerCP/Cy5.5.
Purity
Highly Purified
Specificity
Recognizes human CD2.
References
1. Berney S.M, et al. 2000. J Investig Med. 48:102. 2. Ip S.H, et al. 1982. Clin Chem. 28:1905. 3. Ip S.H, et al. 1982. Blood. 60:795. 4. Moingeon P, et al. 1989. Immunol Rev. 111:111. 5. Reinherz E.L, et al. 1989 Cold Spring Harb Symp Quant Biol. 54:611. 6. Springer T.A, et al. 1987. Annu Rev Immunol. 5:223.|7. Verbi W, et al. 1982. Eur J Immunol. 12:81.