CD25 Antibody - Biotin Conjugated
Référence OADB00127
Conditionnement : 1mL
Marque : Aviva Systems Biology
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CD25 Antibody - Biotin Conjugated (OADB00127)
| Datasheets/Manuals | Printable datasheet for anti-CD25 (OADB00127) antibody |
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| Predicted Species Reactivity | Human |
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| Product Format | Lyophilized |
| Clonality | Monoclonal |
| Clone | B-B10 |
| Isotype | IgG1 |
| Host | Mouse |
| Conjugation | Biotin |
| Application | FC |
| Reconstitution and Storage | Reconstitute with 1 mL deionised water Use 10 uL to label 106 cells or 100 uL of whole blood. Stable at +2-8C for six months after reconstitution. For longer storage, freeze aliquots |
| Purification | Ion exchange chromatography |
| Concentration | 100 tests/1mL |
| Preservative | Sodium Azide |
| Specificity | Recognises the Interleukin 2 Receptor α chain (IL-2 Ra), a 55 kDa protein |
| Formulation | Lyophilisated in phosphate-buffered saline with 1% BSA and 0.1% sodium azide |
| Storage Buffer | Lyophilisated in phosphate-buffered saline with 1% BSA and 0.1% sodium azide |
| Reference | Palmer, E. M. et al., J Immunol,2001; 167(2): 749-58. |
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| Gene Symbol | CD25 |
| Gene Full Name | interleukin 2 receptor subunit alpha |
| Alias Symbols | p55, CD25, IL2R, IMD41, TCGFR, IDDM10 |
| NCBI Gene Id | 3559 |
| Protein Name | interleukin-2 receptor subunit alpha |
| Description of Target | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. |
| Uniprot ID | P01589 |
| Protein Accession # | NP_000408.1 |
| Nucleotide Accession # | NM_000417.2 |
| Molecular Weight | 31 kDa |
