CD271 (Tumor necrosis factor receptor superfamily member16) Antibody
Référence MBS857122-0,1mL-AF488
Conditionnement : 0.1mL(AF488)
Marque : MyBiosource
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Western blot analysis on D3 (A) and PC12 (B) using anti-CD271 polyclonal antibody.
CD271 Antibody – Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS857122NGFR p75 or CD271 is a 75kD transmembrane glycoprotein consisting of an extracellular domain which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain, and a cytoplasmic domain. NGFR p75 displays paradoxical functions… More details
Product Overview
Online Datasheet in PDFProduct Name
CD271, Polyclonal Antibody
Full Product Name
CD271 (Tumor necrosis factor receptor superfamily member16) Antibody
Product Gene Name
anti-CD271 antibody
Clonality
Polyclonal
Isotype
IgG
Species Reactivity
Mouse, Rat
Form/Format
Liquid
Purity/Purification
Affinity Purified
Specificity
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of CD271.
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Applications Tested/Suitable for anti-CD271 antibody
Western Blot (WB)
Application Notes for anti-CD271 antibody
WB: 1:2,000~1:5,000
Product References and Citations for anti-CD271 antibody
1 . "Low-affinity nerve-growth factor receptor (p75NTR) can serve as a receptor for rabies virus."Tuffereau C., Benejean J., Blondel D., Kieffer B., Flamand A.EMBO J. 17:7250-7259(1998). 2. "Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry."Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J., Faessler R., Mann M.J. Proteome Res. 7:5314-5326(2008).
Other Notes
Small volumes of anti-CD271 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for CD271 purchase
MBS857122 is an antibody targeting CD271. Also known as CD271 (Tumor necrosis factor receptor superfamily member16) Antibody. Reactive in Mouse, Rat.
Additional Details
NCBI/Uniprot data below describe general gene information for CD271. It may not necessarily be applicable to this product.
NCBI Official Full Name
Tumor necrosis factor receptor superfamily member 16
NCBI Official Synonym Full Names
nerve growth factor receptor (TNFR superfamily, member 16)
NCBI Official Symbol
Ngfr
NCBI Official Synonym Symbols
p75; LNGFR; p75NTR; p75NGFR; Tnfrsf16
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 16
UniProt Synonym Protein Names
Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; CD_antigen: CD271
UniProt Gene Name
Ngfr
UniProt Synonym Gene Names
Tnfrsf16; NGF receptor
NCBI Protein Information
tumor necrosis factor receptor superfamily member 16
UniProt Comments for CD271
Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells (). Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Binds to rabies virus glycoprotein Gs. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Show more Research Articles on CD271
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-CD271 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Axonal Growth Inhibition (RHOA Activation) Pathway antibodies | Axonal Growth Inhibition (RHOA Activation) Pathway Diagram |
| Axonal Growth Stimulation Pathway antibodies | Axonal Growth Stimulation Pathway Diagram |
| Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies | Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram |
| Ceramide Signalling Pathway antibodies | Ceramide Signalling Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| NADE Modulates Death Signalling Pathway antibodies | NADE Modulates Death Signalling Pathway Diagram |
| NF-kB Is Activated And Signals Survival Pathway antibodies | NF-kB Is Activated And Signals Survival Pathway Diagram |
| NFG And ProNGF Binds To P75NTR Pathway antibodies | NFG And ProNGF Binds To P75NTR Pathway Diagram |
| NRAGE Signals Death Through JNK Pathway antibodies | NRAGE Signals Death Through JNK Pathway Diagram |
Organs/Tissues associated with anti-CD271 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >198 publications with CD271 and Brain |
| Skin Antibodies | >49 publications with CD271 and Skin |
| Embryonic Tissue Antibodies | >45 publications with CD271 and Embryonic Tissue |
| Eye Antibodies | >21 publications with CD271 and Eye |
| Dorsal Root Ganglion Antibodies | >19 publications with CD271 and Dorsal Root Ganglion |
| Sympathetic Ganglion Antibodies | >10 publications with CD271 and Sympathetic Ganglion |
| Lung Antibodies | >9 publications with CD271 and Lung |
| Inner Ear Antibodies | >8 publications with CD271 and Inner Ear |
| Bladder Antibodies | >7 publications with CD271 and Bladder |
| Spleen Antibodies | >3 publications with CD271 and Spleen |