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> CD41, CD61 (CD41b, GP2B, GP-IIb, GPIIb, GP3A, GP-IIIa, GPIIIa, GTA, HPA3, Integrin alpha 2b, ITGA2B, Integrin beta 3, ITGB3, Platelet Glycoprotein IIb of IIb/IIIa Complex) (FITC)

CD41, CD61 (CD41b, GP2B, GP-IIb, GPIIb, GP3A, GP-IIIa, GPIIIa, GTA, HPA3, Integrin alpha 2b, ITGA2B, Integrin beta 3, ITGB3, Platelet Glycoprotein IIb of IIb/IIIa Complex) (FITC)

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Référence C2394-35B1-100ug

Conditionnement : 100ug

Marque : US Biological

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Téléphone : +1 850 650 7790

C2394-35B1CD41, CD61 (CD41b, GP2B, GP-IIb, GPIIb, GP3A, GP-IIIa, GPIIIa, GTA, HPA3, Integrin alpha 2b, ITGA2B, Integrin beta 3, ITGB3, Platelet Glycoprotein IIb of IIb/IIIa Complex) (FITC)

Specifications
Clone TypeMonoclonal
Hostmouse
Sourcechicken
IsotypeIgG1
GradeAffinity Purified
ApplicationsFC
CrossreactivityCh
Shipping TempBlue Ice
Storage Temp-20°C

CD41/61 is a heterodimeric cell surface protein that is expressed on chicken thrombocytes and cells of the thrombocyte lineage. Avian thrombocytes are nucleated equivalents of mammalian platelets that play a role in coagulation and phagocytosis.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: Neat-1:2; 10ul labels 10e6 cells in 100ul
Optimal dilutions to be determined by the researcher.

Hybridoma:
X63/A63-653 myeloma cells with spleen cells from Balb/c mice.

Storage and Stability:
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Mab|Isotype: IgG1|Clone No: 10B1565 (11C3)|Host: mouse|Source: chicken|Concentration: ~0.1mg/ml|Form: Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).|Purity: Purified by Protein G affinity chromatography.|Immunogen: Peripheral blood leukocytes from white leghorn chicken.|Specificity: Recognizes the chicken integrin CD41/61. Reported to induce thrombocyte activation.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Peripheral blood leukocytes from white leghorn chicken.
Form
Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes the chicken integrin CD41/61. Reported to induce thrombocyte activation.
References
1. Lacoste-Eleaume, A.S. et al. (1994) Exp. Cell. Res. 213: 198 - 209. 2. Corbel, C. et al. (2002) Int. J. Dev. 46: 827 - 830. 3. Del Cacho, E. et al. (2008) J Immunol Methods. 334: 59-69. 4. Del Cacho, E. et al. (2009) Vet Immunol Immunopathol. 129: 66-75. 5. Ody, C. et al. (1999) Blood. 93: 2898-906. 6. Chaussé, A.M. et al. (2011) Infect Immun. 79: 3445-54.