CD46 Antibody - PE Conjugated
Référence OASA02110
Conditionnement : 25Tests/0.25ml
Marque : Aviva Systems Biology
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CD46 Antibody - PE Conjugated (OASA02110)
| Datasheets/Manuals | Printable datasheet for anti-CD46 antibody - OASA02110 |
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| Predicted Species Reactivity | Human |
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| Product Format | Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilised |
| Clonality | Monoclonal |
| Clone | MEM-258 |
| Isotype | IgG1 |
| Host | Mouse |
| Conjugation | R-PE |
| Application | FC |
| :: | Preparation: Purified IgG prepared by affinity chromatography on Protein A Preservative Stabilisers: 0.09% - Sodium Azide 1% - Bovine Serum Albumin |
| :: | Approx Protein Conc: IgG concentration 0.1 mg/ml Buffer Solutions: Phosphate buffered saline |
| Reconstitution and Storage | Reconstitution: Reconstitute in 0.25 ml distilled water Storage: Store at +4oC. DO NOT FREEZE This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Immunogen | The immunogen for anti-CD46 antibody: hPB-ALL cell line |
| Predicted Homology Based on Immunogen Sequence | Human |
| Specificity | CD46 |
| Application Info | Flow Cytometry: Neat |
| Application Data | Application #1: Staining of human peripheral blood lymphocytes with Mouse anti Human CD46:FITC  Application #2: Staining of human peripheral blood granulocytes with Mouse anti Human CD46: Alexa Fluor 647  Application #3: Staining of human peripheral blood lymphocytes with Mouse anti Human CD46  Application #4: Staining of human peripheral blood lymphocytes with Mouse anti Human CD46:RPE  |
| Reference | 1. Sirena, D. et al. (2004) The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3. J. Virol. 78:4454-4462. 2. Fremeaux-Bacchi. et al. (2006) Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical Hemolytic Uremic Syndrome. J. Am. Soc. Nephrol. 17:2017-2025. 3. Fleischli, C. et al. (2005) The distal short consensus repeats 1 and 2 of the membrane cofactor protein CD46 and their distance from the cell membrane determine productive entry of species B adenovirus serotype 35. J Virol. 79:10013-22. 4. Sweigard, J.H. et al. (2010) Adenovirus vectors targeting distinct cell types in the retina. Invest Ophthalmol Vis Sci. 51:2219-28. |
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| Gene Symbol | CD46 |
| Alias Symbols | MCP, TLX, AHUS2, MIC10, TRA2.10, MGC26544, CD46 |
| NCBI Gene Id | 4197184 |
| Protein Name | Membrane cofactor protein |
| Description of Target | MOUSE ANTI HUMAN CD46:RPE |
| Uniprot ID | P15529 |
| Protein Accession # | NP_002380.3 |
| Protein Size (# AA) | 392 |
