CD79a (B lymphocyte-specific MB1 protein, B Cell antigen receptor complex-associated protein alpha chain, CD79a molecule immunoglobulin associated alpha, Ig-alpha, IGA, IgM-alpha, Immunoglobulin-associated alpha, Ly54, MB-1 membrane glycoprotein, Membrane
Référence MBS6122903-5x0,1mL
Conditionnement : 5x0.1mL
Marque : MyBiosource
CD79a (B lymphocyte-specific MB1 protein, B Cell antigen receptor complex-associated protein alpha chain, CD79a molecule immunoglobulin associated alpha, Ig-alpha, IGA, IgM-alpha, Immunoglobulin-associated alpha, Ly54, MB-1 membrane glycoprotein, Membrane
CD79a Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6122903MBS6122903 is an antibody targeting CD79a. Also known as CD79a (B lymphocyte-specific MB1 protein, B Cell antigen receptor complex-associated protein alpha chain, CD79a molecule immunoglobulin associated alpha, Ig-alpha, IGA, IgM-alpha,… More details
Product Overview
Online Datasheet in PDFProduct Name
CD79a, Monoclonal Antibody
Full Product Name
CD79a (B lymphocyte-specific MB1 protein, B Cell antigen receptor complex-associated protein alpha chain, CD79a molecule immunoglobulin associated alpha, Ig-alpha, IGA, IgM-alpha, Immunoglobulin-associated alpha, Ly54, MB-1 membrane glycoprotein, Membrane
Product Gene Name
anti-CD79a antibody
Product Synonym Names
B lymphocyte-specific MB1 protein; B-cell antigen receptor complex-associated protein alpha chain; CD79a molecule immunoglobulin associated alpha; Ig-alpha; IGA; IgM-alpha; Immunoglobulin-associated alpha; Ly54; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
JCB117, HM47/A9
Host
Mouse
Species Reactivity
Bovine, Human, Monkey, Mouse, Porcine, Rat
Form/Format
Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A/G Affinity Chromatography.
Specificity
Recognizes human CD79a. Species Crossreactivity: monkey, porcine, bovine, mouse, and rat. Others not known.
Preparation and Storage
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing alkaline phosphatase conjugates will result in a substantial loss of activity.
Molecular Weight
25,038 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (42381190..42385439). Location: 19q13.2
OMIM
112205
Immunogen
A synthetic peptide corresponding to aa202-216 (GTYQDVGSLNIADVQ) of human CD79a protein (JCB117 and HM47/A9). Cellular Localization: Cell surface
Conjugate
AP
Positive Control
Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
Product Categories/Family for anti-CD79a antibody
Antibodies; CD Markers
Applications Tested/Suitable for anti-CD79a antibody
Immunofluorescence (IF), Immunohistochemistry (IHC) Frozen/Paraffin, Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-CD79a antibody
IHC-F/P: 0.5-1ug/ml for 30 minutes at RT
IP: 0.5-1ug/500ug protein lysate
IF: 0.5-1ug/ml
WB: 0.5-1ug/ml
Applications are based on unconjugated antibody.
IP: 0.5-1ug/500ug protein lysate
IF: 0.5-1ug/ml
WB: 0.5-1ug/ml
Applications are based on unconjugated antibody.
Product References and Citations for anti-CD79a antibody
1. Mason, DY, et al. 1995. Blood 86: 1453-1459.
Other Notes
Small volumes of anti-CD79a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for CD79a. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
B-cell antigen receptor complex-associated protein alpha chain isoform 1
NCBI Official Synonym Full Names
CD79a molecule, immunoglobulin-associated alpha
NCBI Official Symbol
CD79A
NCBI Official Synonym Symbols
IGA; MB-1
UniProt Protein Name
B-cell antigen receptor complex-associated protein alpha chain
UniProt Synonym Protein Names
Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein
Protein Family
B-cell antigen receptor complex-associated protein
UniProt Gene Name
CD79A
UniProt Synonym Gene Names
IGA; MB1
UniProt Entry Name
CD79A_HUMAN
NCBI Protein Information
B-cell antigen receptor complex-associated protein alpha chain; ig-alpha; MB-1 membrane glycoprotein; surface IgM-associated protein; CD79a antigen (immunoglobulin-associated alpha); membrane-bound immunoglobulin-associated protein
NCBI Summary for CD79a
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for CD79a
Ig-alpha: an integral membrane protein that associates with surface immunoglobulin B lymphocyte antigen receptor multimeric complex. Surface Ig non-covalently associates with 2 other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. Two alternatively spliced isoforms have been described.
Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: multivesicular body; integral to membrane; plasma membrane; B cell receptor complex; lipid raft; external side of plasma membrane
Molecular Function: transmembrane receptor activity
Biological Process: B cell proliferation; B cell receptor signaling pathway; B cell activation; B cell differentiation
Disease: Agammaglobulinemia 3, Autosomal Recessive
Show more Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: multivesicular body; integral to membrane; plasma membrane; B cell receptor complex; lipid raft; external side of plasma membrane
Molecular Function: transmembrane receptor activity
Biological Process: B cell proliferation; B cell receptor signaling pathway; B cell activation; B cell differentiation
Disease: Agammaglobulinemia 3, Autosomal Recessive
Research Articles on CD79a
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-CD79a antibody
| Reference Product | PubMed Publications |
|---|---|
| CD79B antibody | >570 publications with CD79a and CD79B |
| CD5 antibody | >153 publications with CD79a and CD5 |
| CD19 antibody | >134 publications with CD79a and CD19 |
| SYK antibody | >34 publications with CD79a and SYK |
| LYN antibody | >22 publications with CD79a and LYN |
| FYN antibody | >10 publications with CD79a and FYN |
| BLNK antibody | >10 publications with CD79a and BLNK |
| BLK antibody | >5 publications with CD79a and BLK |
| IGHM antibody | >4 publications with CD79a and IGHM |
| PTPN6 antibody | >4 publications with CD79a and PTPN6 |
Pathways associated with anti-CD79a antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Antigen Activates B Cell Receptor Leading To Generation Of Second Messengers Pathway antibodies | Antigen Activates B Cell Receptor Leading To Generation Of Second Messengers Pathway Diagram |
| B Cell Receptor Signaling Pathway antibodies | B Cell Receptor Signaling Pathway Diagram |
| B Cell Receptor Signaling Pathway antibodies | B Cell Receptor Signaling Pathway Diagram |
| B Cell Receptor Signaling Pathway antibodies | B Cell Receptor Signaling Pathway Diagram |
| BCR Signaling Pathway antibodies | BCR Signaling Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Primary Immunodeficiency Pathway antibodies | Primary Immunodeficiency Pathway Diagram |
| Primary Immunodeficiency Pathway antibodies | Primary Immunodeficiency Pathway Diagram |
| Signaling By The B Cell Receptor (BCR) Pathway antibodies | Signaling By The B Cell Receptor (BCR) Pathway Diagram |
Diseases associated with anti-CD79a antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >738 publications with CD79a and Neoplasms |
| Lymphoma Antibodies | >641 publications with CD79a and Lymphoma |
| Skin Neoplasms Antibodies | >78 publications with CD79a and Skin Neoplasms |
| Neoplasms, Experimental Antibodies | >69 publications with CD79a and Neoplasms, Experimental |
| Cardiovascular Diseases Antibodies | >47 publications with CD79a and Cardiovascular Diseases |
| Inflammation Antibodies | >41 publications with CD79a and Inflammation |
| Hyperplasia Antibodies | >38 publications with CD79a and Hyperplasia |
| Liver Diseases Antibodies | >38 publications with CD79a and Liver Diseases |
| Necrosis Antibodies | >37 publications with CD79a and Necrosis |
| Multiple Myeloma Antibodies | >36 publications with CD79a and Multiple Myeloma |
Organs/Tissues associated with anti-CD79a antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >530 publications with CD79a and Blood |
| Lymph Node Antibodies | >206 publications with CD79a and Lymph Node |
| Lymph Antibodies | >194 publications with CD79a and Lymph |
| Spleen Antibodies | >82 publications with CD79a and Spleen |
| Liver Antibodies | >77 publications with CD79a and Liver |
| Lung Antibodies | >47 publications with CD79a and Lung |
| Intestine Antibodies | >40 publications with CD79a and Intestine |
| Thymus Antibodies | >30 publications with CD79a and Thymus |
| Mouth Antibodies | >21 publications with CD79a and Mouth |
| Heart Antibodies | >19 publications with CD79a and Heart |



