CD79a (CD 79a, CD79A Antigen Immunoglobulin Associated alpha, CD79a Molecule Immunoglobulin Associated alpha, B Lymphocyte Specific MB1 Protein, B cell Antigen Receptor Complex Associated Protein alpha Chain, IGA, Ig alpha, Immunoglobulin Associated Alpha, Ly54, MB 1, MB 1 Membrane Glycoprotein, MB1, MB1 Membrane Glycoprotein, Membrane Bound Immunoglobulin Associated Protein, Surface IgM Associated Protein) (PE)

CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilutions:
Flow Cytometry: Neat; 10ul labels 10e6 cells in 100ul. Membrane permeabilization is required.
Optimal dilutions to be determined by the researcher.

Hybridoma:
Sp2/0 myeloma cells with spleen cells from Balb/c mice.

Storage and Stability:
Store product at 4°C before and after reconstitution. DO NOT FREEZE! Lyophilized and reconstituted products are stable for 12 months at 4°C after receipt. Reconstitute lyophilized powder with sterile ddH2O prior to use and store remainder as an undiluted liquid. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product centrifuge the original vial prior to removing the cap.