CDKN1C Antibody
Référence OASG05596
Conditionnement : 100ul
Marque : Aviva Systems Biology
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CDKN1C Antibody (OASG05596)
| Datasheets/Manuals | Printable datasheet for anti-CDKN1C (OASG05596) antibody |
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| Predicted Species Reactivity | Human, Mouse |
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| Product Format | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | WB, IF |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | Synthesized peptide derived from human p57 around the non-phosphorylation site of T310. Location: 250-330aa. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Specificity | p57 Polyclonal Antibody detects endogenous levels of p57 protein. |
| Application Info | WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000; |
| Gene Symbol | CDKN1C |
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| Gene Full Name | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| Alias Symbols | BWS, WBS, p57, BWCR, KIP2, p57Kip2 |
| NCBI Gene Id | 1028; 12577; |
| Description of Target | This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. |
| Uniprot ID | P49918, P49919 |
| Molecular Weight | 32 kDa |
