CDT1 Antibody - C-terminal region - HRP
Référence ARP46350_P050-HRP
Conditionnement : 100ul
Marque : Aviva Systems Biology
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CDT1 Antibody - C-terminal region : HRP (ARP46350_P050-HRP)
| Datasheets/Manuals | Printable datasheet for anti-CDT1 (ARP46350_P050-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Yeast |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | IHC, WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human CDT1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 93%; Dog: 77%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Yeast: 85% |
| Peptide Sequence | Synthetic peptide located within the following region: PATPPATPPAASPSALKGVSQDLLERIRAKEAQKQLAQMTRCPEQEQRLQ |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-CDT1 (ARP46350_P050-HRP) antibody is Catalog # AAP46350 (Previous Catalog # AAPP27136) |
| Reference | Hu,J. (2006) J. Biol. Chem. 281 (7), 3753-3756 |
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| Gene Symbol | CDT1 |
| Gene Full Name | Chromatin licensing and DNA replication factor 1 |
| Alias Symbols | DUP, RIS2 |
| NCBI Gene Id | 81620 |
| Protein Name | DNA replication factor Cdt1 |
| Description of Target | CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene. |
| Uniprot ID | Q9H211 |
| Protein Accession # | NP_112190 |
| Nucleotide Accession # | NM_030928 |
| Protein Size (# AA) | 546 |
| Molecular Weight | 60kDa |
| Protein Interactions | FBXO31; SKP1; RBX1; CUL1; DTL; PCNA; HECW2; CDK2; CDC6; CDC5L; ORC2; ORC1; GMNN; DGCR8; UBC; SKP2; CDK1; CCNB1; CCNA2; FOXO3; DDB1; COPS5; CUL4A; CUL4B; SMARCA5; MCM6; MAPK8; MAPK1; HDAC11; KAT7; CCNA1; DDB2; CDK4; CCNE1; TP63; TP73; EP300; KAT2B; CDT1; U |
