Cephalosporin C Zinc Salt [59143-60-1]

An antibiotic used to study the effect of transpeptidase expression, binding and inhibition on bacterial cell wall mucopeptide synthesis. Cephalosporin C is a fungal metabolite and cephalosporin antibiotic that has been found in Cephalosporium. It is active against a variety of bacteria, including S. pyogenes, C. diphtheriae, E. coli, and H. influenzae (MICs = 31, 15.6, 125, and 31ug/ml, respectively), as well as clinical isolates of N. gonorrhoeae (MICs = 1.9-15.6ug/ml). Formulations containing cephalosporin C have been used in the treatment of various bacterial infections.

Synonyms:
(6R,7R)-3-[(Acetyloxy)methyl]-7-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid zinc salt; , [6R-[6a,7b(R*)]]-3-[(Acetyloxy)methyl]-7-[(5-amino-5-carboxy-1-oxopentyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid zinc salt

CAS No:
59143-60-1

Molecular Formula:
C16H19N3O8SZn

Molecular Weight:
478.78

Appearance:
White to pale yellow solid

Purity:
≥95%

Melting Point:
240-242°C (dec.)

Solubility:
Aqueous Acid (Slightly)

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.