Chicken CD8aC Antibody : APC
Référence OASB02391
Conditionnement : 0.1mg
Marque : Aviva Systems Biology
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Chicken CD8aC Antibody : APC (OASB02391)
| Datasheets/Manuals | Printable datasheet for Chicken CD8aC Antibody : APC (OASB02391) |
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| Tested Species Reactivity | Chicken |
|---|---|
| Predicted Species Reactivity | Chicken |
| Product Format | Liquid. Phosphate buffered saline containing 0.1% sodium azide and a stabilizer |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugation | APC |
| Application | FC |
| Additional Information | Description: In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two alpha chains and (ii) a heterodimer of an alpha chain and a beta chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8 alpha- and CD8 beta-chains, a relatively large proportion of the CD8+ TCR gamma/delta cells in the spleens of embryos and young chicks express only the alpha-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCR gamma/delta CD8 alpha/beta cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 15% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody CT-8 recognizes the CD8 alpha chain and has been shown to react to a polymorphic determinant in turkey. |
| Reconstitution and Storage | Store at 2-8C |
| Immunogen | Chicken thymocytes and Ig-negative blood leukocytes |
| Concentration | 0.1 mg/mL |
| Specificity | CD8a |
| Gene Symbol | CD8A, LOC100126556, CD8A |
|---|---|
| Alias Symbols | CD8 |
| NCBI Gene Id | 403158; 100126556; 102085944 |
| Protein Name | T-cell surface glycoprotein CD8 alpha chain |
| Uniprot ID | F1NXT4, A7WPR7, A0A2H5BF78 |
| Protein Accession # | XP_015141371.1 |
| Nucleotide Accession # | XM_015285885.1 |
