D-N-Acetylgalactosamine [1811-31-0]
Référence T4708-500mg
Conditionnement : 500mg
Marque : TargetMol
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D-N-Acetylgalactosamine
(Synonyms: N-Acetyl-D-galactosamine, D-GalNAc) Copy Product Info
D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins).
Cas No. 1811-31-0
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.93%
Appearance:Solid
Color:White
COA HNMR LCMS
Product Introduction
D-N-Acetylgalactosamine AI Summary
D-N-Acetylgalactosamine shows acceptor substrate specificity towards Fucosyltransferase for the galactosides of GlcNAc with beta 1,3 or beta 1,4-linkages, with a relative activity of 4.0. It exhibits anticryptosporidial activity against Cryptosporidium parvum GCH1 and Cryptosporidium hominis TU502, with a MIC of 3100000.0 nM for both strains in rabbit erythrocytes hemagglutination assays. Additionally, it inhibits Cryptosporidium parvum recombinant Galactose/N-acetylgalactosamine-specific lectin binding to Caco2A cells with an IC50 of 6500000.0 nM, rated at 2.0 relative to galactose. D-N-Acetylgalactosamine also inhibits D-GalNAc-PAA binding to human recombinant ASGPR1 by competitive solid-phase binding assay, with an IC50 ratio of 1.0. Moreover, it binds to the V5-His tagged FIBCD1 ecto-domain (residues 54 to 461) and reduces the binding between FIBCD1 and acetylated BSA in ELISA with an IC50 of 5000000.0 nM, showing a ratio of 0.4 relative to the control..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins). |
| Synonyms | N-Acetyl-D-galactosamine, D-GalNAc |
| Molecular Weight | 221.21 |
| Formula | C8H15NO6 |
| Cas No. | 1811-31-0 |
| Smiles | OC[C@@H](O)[C@H](O)[C@H](O)[C@H](C=O)NC(C)=O |
| Relative Density. | 1.423 g/cm3 (Predicted) |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 250 mg/mL (1130.15 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+90% Saline: 10 mg/mL (45.21 mM), Suspension. 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.04 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||