Dynein, Cytoplasmic, 74kD Intermediate Chains (AP)

Référence MBS6241665-5x0,1mL

Conditionnement : 5x0.1mL

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Dynein, Cytoplasmic, 74kD Intermediate Chains (AP)

DYNC1I1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6241665

MBS6241665 is an antibody targeting DYNC1I1. Also known as Dynein, Cytoplasmic, 74kD Intermediate Chains (AP). Reactive in Bovine, Drosophila, Mouse, Rat, Sheep, Xenopus. Host: Mouse. More details

Product Overview

Online Datasheet in PDF
Product Name
Dynein (DYNC1I1), Monoclonal Antibody
Full Product Name
Dynein, Cytoplasmic, 74kD Intermediate Chains (AP)
Product Gene Name
anti-DYNC1I1 antibody
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
2Q46
Host
Mouse
Species Reactivity
Bovine, Drosophila, Mouse, Rat, Sheep, Xenopus
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase.
Purity/Purification
Purified
Specificity
Recognizes all known forms of the Mr 74kD intermediate chain subunit (IC74) of mammaliam cytoplasmic dynein. The antigenic site has been localized to the first 60 amino acids of the amino terminal portion of the molecule (a region conserved in both IC74 genes). Species Crossreactivity: Rat, mouse, bovine, sheep, fish, Drosophila and Xenopus. Does not react with squid.
Preparation and Storage
Store at 4 degree C. Do Not Freeze.
Molecular Weight
68,556 Da
3D Structure
ModBase 3D Structure for Q29RQ3
Immunogen
Bovine brain cytoplasmic dynein
Conjugate
AP

Product Categories/Family for anti-DYNC1I1 antibody

Antibodies; Proteins
Applications Tested/Suitable for anti-DYNC1I1 antibody
Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB)

Testing Data of anti-DYNC1I1 antibody

1:500 dilution detected DYNEIN on 10ug of A431 lysates. A431 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with DYNEIN (1:500 dilution of this lot). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates protein DYNEIN (~74kD)
Mouse Anti-DYNC1I1 Monoclonal Antibody – Cat# MBS6241665

Product References and Citations for anti-DYNC1I1 antibody

1. Journal of Cell Biology 127: 1671-1682 (1994). 2. PNAS USA 93: 141-144 (1996). 3. J. Biological Chemistry 271: 1687-1694 (1996). 4. Mol. Biology Cell 7: 331-343 (1996). 5. Journal of Cell Biology 118: 1133-1143 (1992). 6. Tai, A.W., et al., Cell 97: 877-887 (1999). 7. Reese, E.L. and Haimo, L.T., J. Cell Biology 151: 155-165 (2000). 8. Duncan, J.E. and Warrior, R., Current Biology 12: 1982-1991 (2002). 9. Hafezparast, M., et al., Science 300: 808-812 (2003). 10. Okuno, S., et al., J. Neuroscience 24: 7879-7887 (2004).

Other Notes

Small volumes of anti-DYNC1I1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DYNC1I1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cytoplasmic dynein 1 intermediate chain 1
NCBI Official Synonym Full Names
dynein, cytoplasmic 1, intermediate chain 1<
NCBI Official Symbol
DYNC1I1
NCBI Official Synonym Symbols
DH IC-1
UniProt Protein Name
Cytoplasmic dynein 1 intermediate chain 1
UniProt Synonym Protein Names
Cytoplasmic dynein intermediate chain 1; Dynein intermediate chain 1, cytosolic; DH IC-1
Protein Family
Cytoplasmic dynein
UniProt Gene Name
DYNC1I1
UniProt Synonym Gene Names
DH IC-1
UniProt Entry Name
DC1I1_BOVIN
NCBI Protein Information
cytoplasmic dynein 1 intermediate chain 1; dynein intermediate chain 1, cytosolic; cytoplasmic dynein intermediate chain 1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DYNC1I1 antibody

 Reference Product  PubMed Publications
 DYNLL1 antibody  >1 publications with DYNC1I1 and DYNLL1

Pathways associated with anti-DYNC1I1 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 MHC Class II Antigen Presentation Pathway antibodies  MHC Class II Antigen Presentation Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
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 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram
 Vasopressin-regulated Water Reabsorption Pathway antibodies  Vasopressin-regulated Water Reabsorption Pathway Diagram

Diseases associated with anti-DYNC1I1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with DYNC1I1 and Nervous System Diseases
 Peripheral Nervous System Diseases Antibodies  >2 publications with DYNC1I1 and Peripheral Nervous System Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with DYNC1I1 and Carcinoma, Hepatocellular
 Multiple Myeloma Antibodies  >1 publications with DYNC1I1 and Multiple Myeloma
 Congenital Abnormalities Antibodies  >1 publications with DYNC1I1 and Congenital Abnormalities

Organs/Tissues associated with anti-DYNC1I1 antibody

 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >1 publications with DYNC1I1 and Ovary
 Brain Antibodies  >1 publications with DYNC1I1 and Brain