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Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.

ELOVL6-IN-2 [1067647-43-1]

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Référence NB-64-45554-10mg

Conditionnement : 10mg

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Téléphone : +1 850 650 7790

Marque : Neo Biotech

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ELOVL6-IN-2

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Synonyms:

Catalog No. T9215 Copy Product Info

Purity: 99.43%

ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.

Cas No. 1067647-43-1

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.43%

Appearance:Solid

Color:White

Product Introduction

Bioactivity

Description	ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
Targets & IC50	ELOVL6:34 nM(mouse )
In vivo	ELOVL6-IN-2 potently and proportionally suppressed?the elongation index of fatty acids in the liver in mice[1].

Chemical Properties

Molecular Weight	579.49
Formula	C₂₈H₂₃F₆N₃O₄
Cas No.	1067647-43-1
Smiles	Cc1[nH]n(-c2ccc(OC(F)(F)F)cc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F
Relative Density.	1.49 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 135 mg/mL (232.96 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (5.69 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7257 mL	8.6283 mL	17.2566 mL	86.2828 mL
5 mM	0.3451 mL	1.7257 mL	3.4513 mL	17.2566 mL
10 mM	0.1726 mL	0.8628 mL	1.7257 mL	8.6283 mL
20 mM	0.0863 mL	0.4314 mL	0.8628 mL	4.3141 mL
50 mM	0.0345 mL	0.1726 mL	0.3451 mL	1.7257 mL
100 mM	0.0173 mL	0.0863 mL	0.1726 mL	0.8628 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

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Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

Keywords

selectivepotentplasmaorallyliverInhibitorinhibitELOVL6-IN-2ELOVL-6-IN-2ELOVL6IN2ELOVL6 IN 2ELOVL6dose-proportionally

Related Tags: ELOVL6-IN-2 chemical structure | ELOVL6-IN-2 in vivo | ELOVL6-IN-2 formula | ELOVL6-IN-2 molecular weight

ELOVL6-IN-2 [1067647-43-1]

Référence NB-64-45554-10mg

Contactez votre distributeur local :

Marque : Neo Biotech

Contactez votre distributeur local :

ELOVL6-IN-2

Product Introduction

Calculator

In Vivo Formulation Calculator (Clear solution)

Dose Conversion

Keywords

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