FFN511 (Fluorescent False Neurotransmitter 511, Vesicle Monoamine Transporter (VMAT2) Substrate, FFN511)

A fluorescent false neurotransmitter that acts as an optical tracer that inhibits serotonin binding to VMAT2-containing membranes (IC50 = 1uM). Compound has been used to assess the functional status of TH positive neurons by fluorescent measurement of uptatke and release.

CAS Number:
1004548-96-2

Solubility:
DMSO

Primary Target:
VMAT2

Primary Target IC50:
1u

Molar Mass:
284.35

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.