Fibronectin
Référence MBS8535020-0,1mL-AF546
Conditionnement : 0.1mL(AF546)
Marque : MyBiosource
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Fibronectin (FN) Antibody – Mouse Monoclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8535020MBS8535020 is an antibody targeting FN. Also known as Fibronectin. Reactive in Human, Mouse, Rat. Host: Mouse. More details
Product Overview
Online Datasheet in PDFProduct Name
Fibronectin (FN), Monoclonal Antibody
Full Product Name
Fibronectin
Product Gene Name
anti-FN antibody
Product Synonym Gene Name
FN1
Product Synonym Names
Cold-insoluble globulin; CIG
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3G4
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Purity/Purification
ProA affinity purified
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Applications Tested/Suitable for anti-FN antibody
Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
Other Notes
Small volumes of anti-FN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for FN. It may not necessarily be applicable to this product.
NCBI Official Full Name
fibronectin isoform 8
NCBI Official Synonym Full Names
fibronectin 1
NCBI Official Symbol
FN1
NCBI Official Synonym Symbols
FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; SMDCF
UniProt Protein Name
Fibronectin
UniProt Synonym Protein Names
Cold-insoluble globulin; CIG
Protein Family
Fibronectin
UniProt Gene Name
FN1
UniProt Synonym Gene Names
FN; FN; CIG
NCBI Protein Information
fibronectin
NCBI Summary for FN
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016]
Show more UniProt Comments for FN
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
Show more Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-FN antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| AGE-RAGE Signaling Pathway In Diabetic Complications antibodies | AGE-RAGE Signaling Pathway In Diabetic Complications Diagram |
| AGE-RAGE Signaling Pathway In Diabetic Complications antibodies | AGE-RAGE Signaling Pathway In Diabetic Complications Diagram |
| ARMS-mediated Activation Pathway antibodies | ARMS-mediated Activation Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Amoebiasis Pathway antibodies | Amoebiasis Pathway Diagram |
| Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies | Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram |
| Axon Guidance Pathway antibodies | Axon Guidance Pathway Diagram |
| Bacterial Invasion Of Epithelial Cells Pathway antibodies | Bacterial Invasion Of Epithelial Cells Pathway Diagram |
| Bacterial Invasion Of Epithelial Cells Pathway antibodies | Bacterial Invasion Of Epithelial Cells Pathway Diagram |
| Cell Surface Interactions At The Vascular Wall Pathway antibodies | Cell Surface Interactions At The Vascular Wall Pathway Diagram |
Diseases associated with anti-FN antibody
| Disease Name | Pubmed Publications |
|---|---|
| Carcinoma Antibodies | >83 publications with FN and Carcinoma |
| Fibrosis Antibodies | >38 publications with FN and Fibrosis |
| Inflammation Antibodies | >32 publications with FN and Inflammation |
| Lung Diseases Antibodies | >28 publications with FN and Lung Diseases |
| Cardiovascular Diseases Antibodies | >23 publications with FN and Cardiovascular Diseases |
| Lung Neoplasms Antibodies | >23 publications with FN and Lung Neoplasms |
| Breast Neoplasms Antibodies | >22 publications with FN and Breast Neoplasms |
| Neoplasms, Experimental Antibodies | >21 publications with FN and Neoplasms, Experimental |
| Neoplasm Invasiveness Antibodies | >19 publications with FN and Neoplasm Invasiveness |
| Kidney Diseases Antibodies | >17 publications with FN and Kidney Diseases |
Organs/Tissues associated with anti-FN antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >66 publications with FN and Blood |
| Muscle Antibodies | >38 publications with FN and Muscle |
| Lung Antibodies | >37 publications with FN and Lung |
| Vascular Antibodies | >35 publications with FN and Vascular |
| Liver Antibodies | >30 publications with FN and Liver |
| Bone Antibodies | >30 publications with FN and Bone |
| Kidney Antibodies | >30 publications with FN and Kidney |
| Embryonic Tissue Antibodies | >23 publications with FN and Embryonic Tissue |
| Brain Antibodies | >21 publications with FN and Brain |
| Connective Tissue Antibodies | >21 publications with FN and Connective Tissue |