Finasteride [98319-26-7]

Référence bs-75498C-100mg

Conditionnement : 100mg

Marque : Bioss

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Overview
Catalog # bs-75498c-25mg
Product Name Finasteride
Specifications
Storage Buffer Solid
Storage Condition Stable for 2 years after receipt when stored at +4°C.
Target
Product Information CAS Number: 98319-26-7

Molecular formula: C23H36N2O2

Molecular weight: 372.5

Purity: >98% (HPLC)

Appearance: White to off-white solid.

Solubility: Soluble in DMSO, DMF, ethanol or methanol. Sparingly soluble in water.

InChiKey: DBEPLOCGEIEOCV-WSBQPABSSA-N

SMILES: 09[C@@]12CC[C@H](C(=O)NC(C)(C)C)[C@@]1(C)CC[C@@]1(09)[C@@]2(09)CC[C@@]2(09)NC(=O)C=C[C@]12C
Description Potent, specific and competitive inhibitor of type II 5alpha-reductase (enzyme which converts testosterone to the more potent 5alpha-dihydrotestosterone) [1, 3]. Anticancer compound [2, 6, 7]. Apoptosis modulator [2, 6]. Enhances the action of GABA at GABA(A) receptors, which leads to neurological implications [4]. Inhibit testosterone-induced type I procollagen and TGF-beta1 expression in human scalp dermal fibroblasts in a model of androgenic alopecia [5]. Drug for the treatment of male androgenetic alopecia [8]. Potential role in neuropsychiatric disorders [9]. Shown to reduce L-DOPA-induced dyskinesia in rodent models for Parkinson’s disease [10].