FOXO1/3 Antibody
Référence MBS8583062-0,1mL-AF647
Conditionnement : 0.1mL(AF647)
Marque : MyBiosource
Contactez votre distributeur local :
Téléphone : +1 850 650 7790
FOXO1/3 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8583062MBS8583062 is an antibody targeting FOXO1/3. Also known as FOXO1/3 Antibody. Reactive in Human, Mouse, Rat, Bovine, Pig. Host: Rabbit. Rabbit polyclonal antibody to FOXO1/3 More details
Product Overview
Online Datasheet in PDFProduct Name
FOXO1/3, Polyclonal Antibody
Full Product Name
FOXO1/3 Antibody
Product Gene Name
anti-FOXO1/3 antibody
Product Synonym Gene Name
FOXO1, FOXO3
Product Synonym Names
FOXO1; FKHR; FOXO1A; Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma; FOXO3; FKHRL1; FOXO3A; Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Pig
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of FOXO1/3 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
69,662 Da
Chromosome Location
Chromosome: 13; NC_000013.10 (41129801..41240734, complement). Location: 13q14.1
OMIM
136533
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FOXO1/3. The exact sequence is proprietary.
Product Categories/Family for anti-FOXO1/3 antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-FOXO1/3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-FOXO1/3 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IHC: 1:50-1:200
Other Notes
Small volumes of anti-FOXO1/3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for FOXO1/3. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
forkhead box protein O1
NCBI Official Synonym Full Names
forkhead box O1
NCBI Official Symbol
FOXO1
NCBI Official Synonym Symbols
FKH1; FKHR; FOXO1A
UniProt Protein Name
Forkhead box protein O1
UniProt Synonym Protein Names
Forkhead box protein O1A; Forkhead in rhabdomyosarcoma
UniProt Gene Name
FOXO1
UniProt Synonym Gene Names
FKHR; FOXO1A
UniProt Entry Name
FOXO1_HUMAN
NCBI Protein Information
forkhead box protein O1; forkhead box protein O1A; forkhead, Drosophila, homolog of, in rhabdomyosarcoma
NCBI Summary for FOXO1/3
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for FOXO1/3
FOXO1A: a transcription factor of the forkhead family. A central regulator of metabolism in several cell types. May play an important role in myogenic growth and differentiation, and in the regulation of lipolysis in adipocytes by controlling the expression of adipose triglyceride lipase (ATGL), the rate-limiting lipolytic enzyme. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Contains 1 fork-head domain.
Protein type: Nuclear receptor co-regulator; DNA-binding; Transcription factor; Oncoprotein
Chromosomal Location of Human Ortholog: 13q14.1
Cellular Component: nucleoplasm; mitochondrion; cytoplasm; nucleus; cytosol
Molecular Function: protein binding; protein phosphatase 2A binding; sequence-specific DNA binding; ubiquitin protein ligase binding; chromatin binding
Biological Process: transcription from RNA polymerase II promoter; fat cell differentiation; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; apoptosis; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; thermoregulation; positive regulation of gluconeogenesis; positive regulation of autophagy; epidermal growth factor receptor signaling pathway; blood vessel development; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; negative regulation of fat cell differentiation; negative regulation of stress-activated MAPK cascade; cellular response to starvation; endocrine pancreas development; protein amino acid acetylation; cellular response to insulin stimulus; insulin receptor signaling pathway; positive regulation of protein catabolic process; autophagy; cell glucose homeostasis; innate immune response; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; response to DNA damage stimulus; negative regulation of apoptosis
Disease: Rhabdomyosarcoma 2
Show more Protein type: Nuclear receptor co-regulator; DNA-binding; Transcription factor; Oncoprotein
Chromosomal Location of Human Ortholog: 13q14.1
Cellular Component: nucleoplasm; mitochondrion; cytoplasm; nucleus; cytosol
Molecular Function: protein binding; protein phosphatase 2A binding; sequence-specific DNA binding; ubiquitin protein ligase binding; chromatin binding
Biological Process: transcription from RNA polymerase II promoter; fat cell differentiation; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; apoptosis; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; thermoregulation; positive regulation of gluconeogenesis; positive regulation of autophagy; epidermal growth factor receptor signaling pathway; blood vessel development; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; negative regulation of fat cell differentiation; negative regulation of stress-activated MAPK cascade; cellular response to starvation; endocrine pancreas development; protein amino acid acetylation; cellular response to insulin stimulus; insulin receptor signaling pathway; positive regulation of protein catabolic process; autophagy; cell glucose homeostasis; innate immune response; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; response to DNA damage stimulus; negative regulation of apoptosis
Disease: Rhabdomyosarcoma 2
Research Articles on FOXO1/3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-FOXO1/3 antibody
| Reference Product | PubMed Publications |
|---|---|
| AKT1 antibody | >119 publications with FOXO1/3 and AKT1 |
| SIRT1 antibody | >111 publications with FOXO1/3 and SIRT1 |
| PPARG antibody | >38 publications with FOXO1/3 and PPARG |
| CTNNB1 antibody | >27 publications with FOXO1/3 and CTNNB1 |
| CDKN1A antibody | >21 publications with FOXO1/3 and CDKN1A |
| SRC antibody | >15 publications with FOXO1/3 and SRC |
| SMAD3 antibody | >12 publications with FOXO1/3 and SMAD3 |
| DYRK1A antibody | >7 publications with FOXO1/3 and DYRK1A |
| FOXG1 antibody | >7 publications with FOXO1/3 and FOXG1 |
| HNF4A antibody | >7 publications with FOXO1/3 and HNF4A |
Pathways associated with anti-FOXO1/3 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| AGE/RAGE Pathway antibodies | AGE/RAGE Pathway Diagram |
| AKT Phosphorylates Targets In The Nucleus Pathway antibodies | AKT Phosphorylates Targets In The Nucleus Pathway Diagram |
| AKT-mediated Inactivation Of FOXO1A Pathway antibodies | AKT-mediated Inactivation Of FOXO1A Pathway Diagram |
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Adipogenesis Pathway antibodies | Adipogenesis Pathway Diagram |
| Androgen Receptor Signaling Pathway antibodies | Androgen Receptor Signaling Pathway Diagram |
| Angiopoietin Receptor Tie2-mediated Signaling Pathway antibodies | Angiopoietin Receptor Tie2-mediated Signaling Pathway Diagram |
| B Cell Receptor Signaling Pathway antibodies | B Cell Receptor Signaling Pathway Diagram |
| CXCR4-mediated Signaling Events Pathway antibodies | CXCR4-mediated Signaling Events Pathway Diagram |
| Class I PI3K Signaling Events Mediated By Akt Pathway antibodies | Class I PI3K Signaling Events Mediated By Akt Pathway Diagram |
Diseases associated with anti-FOXO1/3 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >404 publications with FOXO1/3 and Neoplasms |
| Insulin Resistance Antibodies | >227 publications with FOXO1/3 and Insulin Resistance |
| Rhabdomyosarcoma, Alveolar Antibodies | >157 publications with FOXO1/3 and Rhabdomyosarcoma, Alveolar |
| Atrophy Antibodies | >93 publications with FOXO1/3 and Atrophy |
| Hyperglycemia Antibodies | >81 publications with FOXO1/3 and Hyperglycemia |
| Fatty Liver Antibodies | >77 publications with FOXO1/3 and Fatty Liver |
| Inflammation Antibodies | >75 publications with FOXO1/3 and Inflammation |
| Cardiovascular Diseases Antibodies | >69 publications with FOXO1/3 and Cardiovascular Diseases |
| Liver Diseases Antibodies | >68 publications with FOXO1/3 and Liver Diseases |
| Necrosis Antibodies | >65 publications with FOXO1/3 and Necrosis |
Organs/Tissues associated with anti-FOXO1/3 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Muscle Antibodies | >366 publications with FOXO1/3 and Muscle |
| Blood Antibodies | >299 publications with FOXO1/3 and Blood |
| Liver Antibodies | >288 publications with FOXO1/3 and Liver |
| Nerve Antibodies | >221 publications with FOXO1/3 and Nerve |
| Brain Antibodies | >121 publications with FOXO1/3 and Brain |
| Vascular Antibodies | >119 publications with FOXO1/3 and Vascular |
| Pancreas Antibodies | >113 publications with FOXO1/3 and Pancreas |
| Heart Antibodies | >74 publications with FOXO1/3 and Heart |
| Bone Antibodies | >65 publications with FOXO1/3 and Bone |
| Embryonic Tissue Antibodies | >52 publications with FOXO1/3 and Embryonic Tissue |