G CSF Protein
Référence OOPA00034
Conditionnement : 2µg
Marque : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for OOPA00034 |
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| Predicted Species Reactivity | Human |
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| Product Format | Colorless, clear and transparent solution. |
| Host | Escherichia Coli. |
| :: | Product Introduction: GCSF is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for this gene. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This csf induces granulocytes. Product Description: Granulocyte Colony Stimulating Factor Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids and having a molecular mass of 18.8kDa. The Pegylated G-CSF is produced by attaching a 20kDa methoxypolyethylene glycol propionaldehyde (mPEG-ALD) to the N-terminal amino acid of G-CSF giving a total molecular mass of 38.8kDa. G-CSF is purified by proprietary chromatographic techniques. |
| Reconstitution and Storage | G-CSF PEG should be stored refrigerated at 2 to 8C. Vials should be kept in theirpackaging to protect from light until the time of use. Shaking and freezing should be avoided. |
| Formulation | G-CSF is supplied in solution (0.69mg/ml) containing 10mM Acetate Buffer (pH 4.0), and 0.004% Polysorbate 80. |
| Purification | Greater than 95.0% as determined by SEC-HPLC. |
| Purity | Greater than 95.0% as determined by SEC-HPLC. |
| Biological Activity | The ED50, calculated by the dose-dependent proliferation of murine NFS-60 indicator cells is less than 0.1 ng/ml, corresponding to a Specific Activity of 10,000,000IU/mg. |
| Gene Symbol | G CSF |
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| Alias Symbols | CSF-3, MGI-1G, GM-CSF beta, Pluripoietin, Filgrastim, Lenograstim, G-CSF, MGC45931, GCSF. |
| Protein Size (# AA) | Recombinant |