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> Glycogen synthase 2 (GYS2) (NM_021957) Human Mass Spec Standard

Glycogen synthase 2 (GYS2) (NM_021957) Human Mass Spec Standard

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Glycogen synthase 2 (GYS2) (NM_021957) Human Mass Spec Standard

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SKU
PH311375
GYS2 MS Standard C13 and N15-labeled recombinant protein (NP_068776)
 

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Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC211375
Predicted MW 81 kDa
Protein Sequence
Protein Sequence
>RC211375 protein sequence
Red=Cloning site Green=Tags(s)

MLRGRSLSVTSLGGLPQWEVEELPVEELLLFEVAWEVTNKVGGIYTVIQTKAKTTADEWGENYFLIGPYF
EHNMKTQVEQCEPVNDAVRRAVDAMNKHGCQVHFGRWLIEGSPYVVLFDIGYSAWNLDRWKGDLWEACSV
GIPYHDREANDMLIFGSLTAWFLKEVTDHADGKYVVAQFHEWQAGIGLILSRARKLPIATIFTTHATLLG
RYLCAANIDFYNHLDKFNIDKEAGERQIYHRYCMERASVHCAHVFTTVSEITAIEAEHMLKRKPDVVTPN
GLNVKKFSAVHEFQNLHAMYKARIQDFVRGHFYGHLDFDLEKTLFLFIAGRYEFSNKGADIFLESLSRLN
FLLRMHKSDITVVVFFIMPAKTNNFNVETLKGQAVRKQLWDVAHSVKEKFGKKLYDALLRGEIPDLNDIL
DRDDLTIMKRAIFSTQRQSLPPVTTHNMIDDSTDPILSTIRRIGLFNNRTDRVKVILHPEFLSSTSPLLP
MDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMQEHVADPTAYGIYIVDRRFRSP
DDSCNQLTKFLYGFCKQSRRQRIIQRNRTERLSDLLDWRYLGRYYQHARHLTLSRAFPDKFHVELTSPPT
TEGFKYPRPSSVPPSPSGSQASSPQSSDVEDEVEDERYDEEEEAERDRLNIKSPFSLSHVPHGKKKLHGE
YKN

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_068776
RefSeq Size 3132
RefSeq ORF 2109
Locus ID 2998
UniProt ID P54840
Cytogenetics 12p12.1
Summary The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content. provided by RefSeq, Dec 2009
Protein Pathways Insulin signaling pathway, Starch and sucrose metabolism
FAQs
  • Protein FAQs
SDS
SKU Description Size
LC411861 Lyophilized GYS2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
LY411861 Transient overexpression lysate of glycogen synthase 2 (liver) (GYS2) (as WB positive control) 100 ug
TP311375 Recombinant protein of human glycogen synthase 2 (liver) (GYS2), 20 µg 20 ug

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