Granulocyte Colony Stimulating Factor (G-CSF)
Référence MBS343036-5x1mg
Conditionnement : 5x1mg
Marque : MyBiosource
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Granulocyte Colony Stimulating Factor (G-CSF) Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS343036G-CSF is a growth factor and/or cytokine produced by the endothelium, macrophages and a number of other immune cells. G-CSF stimulates the bone marrow to produce granulocytes and also to stimulate the survival, proliferation, differentiation and function of… More details
Product Overview
Online Datasheet in PDFProduct Name
Granulocyte Colony Stimulating Factor (G-CSF), Recombinant Protein
Full Product Name
Granulocyte Colony Stimulating Factor (G-CSF)
Product Gene Name
G-CSF recombinant protein
Product Synonym Names
Granulocyte Colony Stimulating Factor, CSF-3, MGI-1G, GM-CSF beta, Pluripoietin, Filgrastim, Lenograstim, G-CSF, MGC45931, GCSF.
Form/Format
Liquid; 20 mM Tris-HCl pH 8.0, 50% Glycerol
Purity/Purification
>95%
Concentration
0.8 mg/ml (lot specific)
Preparation and Storage
Store at -20°C.
Vials should be centrifuged briefly before opening to ensure contents are not lost when removing cap.
Vials should be centrifuged briefly before opening to ensure contents are not lost when removing cap.
Molecular Weight
23.19 kDa
OMIM
138970
Product Categories/Family for G-CSF recombinant protein
Recombinant Proteins; G-CSF
ISO Certification
Manufactured in an ISO 13485:2016 Certified Laboratory.
Product References and Citations for G-CSF recombinant protein
Nagata, S. (1989), Bioessays 10(4): 113-117.
Other Notes
Small volumes of G-CSF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for G-CSF purchase
MBS343036 is a recombinant protein targeting G-CSF. Also known as Granulocyte Colony Stimulating Factor (G-CSF).
Additional Details
NCBI/Uniprot data below describe general gene information for G-CSF. It may not necessarily be applicable to this product.
NCBI Official Full Name
granulocyte colony stimulating factor, partial
NCBI Official Synonym Full Names
colony stimulating factor 3
NCBI Official Symbol
CSF3
NCBI Official Synonym Symbols
GCSF; CSF3OS; C17orf33
UniProt Protein Name
Granulocyte colony-stimulating factor
UniProt Synonym Protein Names
Pluripoietin; INN: Filgrastim; INN: Lenograstim
Protein Family
Granulocyte colony-stimulating factor
UniProt Gene Name
CSF3
UniProt Synonym Gene Names
C17orf33; GCSF; G-CSF
UniProt Entry Name
CSF3_HUMAN
NCBI Protein Information
granulocyte colony-stimulating factor
NCBI Summary for G-CSF
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
UniProt Comments for G-CSF
G-CSF: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. Belongs to the IL-6 superfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation; Cytokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q11.2-q12
Cellular Component: extracellular region
Molecular Function: cytokine activity; enzyme binding; growth factor activity
Biological Process: multicellular organismal development; positive regulation of actin filament polymerization; positive regulation of myeloid cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein binding; positive regulation of protein kinase B signaling cascade; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter
Show more Protein type: Cell cycle regulation; Cytokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q11.2-q12
Cellular Component: extracellular region
Molecular Function: cytokine activity; enzyme binding; growth factor activity
Biological Process: multicellular organismal development; positive regulation of actin filament polymerization; positive regulation of myeloid cell differentiation; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein binding; positive regulation of protein kinase B signaling cascade; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter
Research Articles on G-CSF
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with G-CSF recombinant protein
| Products by Pathway | Pathway Diagram |
|---|---|
| Cytokine Signaling In Immune System Pathway antibodies | Cytokine Signaling In Immune System Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokine-cytokine Receptor Interaction Pathway antibodies | Cytokine-cytokine Receptor Interaction Pathway Diagram |
| Cytokines And Inflammatory Response Pathway antibodies | Cytokines And Inflammatory Response Pathway Diagram |
| Hematopoietic Cell Lineage Pathway antibodies | Hematopoietic Cell Lineage Pathway Diagram |
| Hematopoietic Cell Lineage Pathway antibodies | Hematopoietic Cell Lineage Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
| Jak-STAT Signaling Pathway antibodies | Jak-STAT Signaling Pathway Diagram |
| Jak-STAT Signaling Pathway antibodies | Jak-STAT Signaling Pathway Diagram |
| Malaria Pathway antibodies | Malaria Pathway Diagram |
Diseases associated with G-CSF recombinant protein
| Disease Name | Pubmed Publications |
|---|---|
| Disease Susceptibility Antibodies | >8 publications with G-CSF and Disease Susceptibility |
| Nervous System Diseases Antibodies | >8 publications with G-CSF and Nervous System Diseases |
| Neutropenia Antibodies | >5 publications with G-CSF and Neutropenia |
| Breast Neoplasms Antibodies | >3 publications with G-CSF and Breast Neoplasms |
| Leukemia, Myeloid, Acute Antibodies | >3 publications with G-CSF and Leukemia, Myeloid, Acute |
| Neoplasm Metastasis Antibodies | >3 publications with G-CSF and Neoplasm Metastasis |
| Leukopenia Antibodies | >3 publications with G-CSF and Leukopenia |
| Gastrointestinal Diseases Antibodies | >2 publications with G-CSF and Gastrointestinal Diseases |
| Brain Injuries Antibodies | >2 publications with G-CSF and Brain Injuries |
| Anemia Antibodies | >2 publications with G-CSF and Anemia |
Organs/Tissues associated with G-CSF recombinant protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Lung Antibodies | >11 publications with G-CSF and Lung |
| Muscle Antibodies | >9 publications with G-CSF and Muscle |
| Skin Antibodies | >9 publications with G-CSF and Skin |
| Brain Antibodies | >6 publications with G-CSF and Brain |
| Uterus Antibodies | >5 publications with G-CSF and Uterus |
| Intestine Antibodies | >3 publications with G-CSF and Intestine |
| Liver Antibodies | >2 publications with G-CSF and Liver |
| Uncharacterized Tissue Antibodies | >1 publications with G-CSF and Uncharacterized Tissue |