Réactifs et instruments pour l'immunologie, la biologie cellulaire et la biologie moléculaire.
 
> GSK-3484862 [2170136-65-7]

GSK-3484862 [2170136-65-7]

Imprimer Imprimer
Identifiez-vous

Référence orb1309609-1mg

Conditionnement : 1mg

Marque : Biorbyt

Contactez votre distributeur local :


Téléphone : +1 850 650 7790

GSK-3484862

SKU: orb1309609

Description

GSK-3484862 is a non-covalent, cell-active DNMT1 inhibitor that induces global DNA demethylation. It is a valuable chemical probe for epigenetic research in cancer biology and stem cell studies, demonstrating activity in both cellular and in vivo models.

Research Area

Epigenetics & Chromatin

Images & Validation

−
GSK-3484862

Key Properties

−
CAS Number2170136-65-7
MW365.45
Purity>99.99% (May vary between batches)
FormulaC19H19N5OS
SMILESCCc1c(C#N)c(S[C@@H](C(N)=O)c2ccccc2)nc(N(C)C)c1C#N
TargetDNA Methyltransferase
SolubilityDMSO:22.5 mg/mL (61.57 mM)

Storage & Handling

−
Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

−
5-Azacytidine, Dnmt1, DNMT1, DNMTs, DNA, DNA Methyltransferase, DNA MTases, DNAMethyltransferase, Inhibitor, inhibit, methyltransferase1, hypomethylation, GSK 3484862, GSK3484862, GSK-3484862, epigenetic, therapies
−
  • (Rac)-GSK-3484862

    (Rac)-GSK-3484862 [orb3218163]

    98.93% (May vary between batches)

    2170136-02-2

    365.45

    C19H19N5OS

    25 mg, 5 mg, 10 mg, 1 mg

Compound Identifiers

PubChem CID
132233666 ↗

Key Properties

−
Failed to load PubChem data

Protocol Information