High Density Lipoprotein (HDL), Human Plasma

Référence MBS173147-10mg

Conditionnement : 10mg

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High Density Lipoprotein (HDL) Native Protein, Human Plasma

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS173147

This HDL (High Density Lipoprotein) protein is purified directly from human plasma rather than recombinantly expressed, providing a native-source standard for lipid metabolism, reverse cholesterol transport, and cardiovascular research. MBS173147 is a protein… More details

Product Overview

Product Name
High Density Lipoprotein (HDL), Protein
Full Product Name
High Density Lipoprotein (HDL), Human Plasma
Product Gene Name
HDL protein
Product Synonym Names
HDL
Form/Format
Frozen Liquid
Preparation and Storage
Ships on dry ice.
Store at -20 degree C for up to 3 months. Store at -70 degree C more than 3 months. Avoid freeze-thaws.
OMIM
142695
Source
Fresh human plasma
Appearance
Amber to orange liquid
Total Cholesterol
3,910 mg/dL
Triglyceride
1,450 mg/dL
HDL Cholesterol
3,250 mg/dL
Triglyceride Ratio
0.37 (Triglyceride/Total Cholesterol)
Electrophoresis
One major band observed, corresponds to HDL (Helena QuickGel® Cholesterol)
Handling
Thaw in a 37 degree C water bath, removing as soon as thawed. Store at 2-8 degree C for up to one week.
Dilute with 0.15 M sodium chloride or another appropriate solution.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Product References and Citations for HDL protein

Nitrated apolipoprotein AI/apolipoprotein AI ratio is increased in diabetic patients with coronary artery disease. Xueying Chen, Ahmed Bakillah, Liye Zhou, Xiaoyue Pan, Florian Hoepfner, Marrit Jacob, Xian-Cheng Jiang, f, Jason Lazar, Axel Schlitt, M.Mahmood Hussain (2016)
Plasma Nitration of High-Density and Low-Density Lipoproteins in Chronic Kidney Disease Patients Receiving Kidney Transplants. Ahmed Bakillah, Fasika Tedla, Isabelle Ayoub, Devon John, Allen J. Norin, M. Mahmood Hussain, and Clinton Brown (2015)

Other Notes

Small volumes of HDL protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HDL purchase

MBS173147 is a protein targeting HDL. Also known as High Density Lipoprotein (HDL), Human Plasma.

Additional Details

NCBI/Uniprot data below describe general gene information for HDL. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
vigilin isoform a
NCBI Official Synonym Full Names
high density lipoprotein binding protein
NCBI Official Symbol
HDLBP
NCBI Official Synonym Symbols
HBP; VGL; PRO2900
UniProt Protein Name
Vigilin
UniProt Synonym Protein Names
High density lipoprotein-binding protein; HDL-binding protein
Protein Family
(S)-2-haloacid dehalogenase
UniProt Gene Name
HDLBP
UniProt Synonym Gene Names
HBP; VGL; HDL-binding protein
UniProt Entry Name
VIGLN_HUMAN
NCBI Protein Information
vigilin; HDL-binding protein; high density lipoprotein-binding protein

NCBI Summary for HDL

The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
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UniProt Comments for HDL

vigilin: a nuclear and cytoplasmic protein that may play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.

Protein type: Lipid-binding; RNA-binding

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: cytoplasm; plasma membrane; nucleus

Molecular Function: protein binding; lipid binding

Biological Process: cholesterol metabolic process; lipid transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with HDL protein

 Disease Name  Pubmed Publications
 Microcephaly Antibodies  >1 publications with HDL and Microcephaly
 Breast Neoplasms Antibodies  >1 publications with HDL and Breast Neoplasms
 Liver Diseases Antibodies  >1 publications with HDL and Liver Diseases
 Nervous System Malformations Antibodies  >1 publications with HDL and Nervous System Malformations
 Immune System Diseases Antibodies  >1 publications with HDL and Immune System Diseases
 Fatty Liver Antibodies  >1 publications with HDL and Fatty Liver
 Congenital Abnormalities Antibodies  >1 publications with HDL and Congenital Abnormalities
 Nervous System Diseases Antibodies  >1 publications with HDL and Nervous System Diseases
 Autistic Disorder Antibodies  >1 publications with HDL and Autistic Disorder

Organs/Tissues associated with HDL protein

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with HDL and Liver
 Bone Antibodies  >1 publications with HDL and Bone
 Ovary Antibodies  >1 publications with HDL and Ovary
 Prostate Antibodies  >1 publications with HDL and Prostate

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