Hisne H2A Acetyl
Référence MBS8535044-0,1mL-APC
Conditionnement : 0.1mL(APC)
Marque : MyBiosource
Hisne H2A Acetyl (H2AFX) Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8535044MBS8535044 is an antibody targeting H2afx. Also known as Hisne H2A Acetyl. Reactive in Broad mammalian, Zebrafish, Drosophila, Xenopus and C. elegans. Host: Rabbit. More details
Product Overview
Online Datasheet in PDFProduct Name
Hisne H2A Acetyl (H2afx), Polyclonal Antibody
Full Product Name
Hisne H2A Acetyl
Product Gene Name
anti-H2afx antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Broad mammalian, Zebrafish, Drosophila, Xenopus and C. elegans
Purity/Purification
Immunogen affinity purified
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Applications Tested/Suitable for anti-H2afx antibody
Western Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
Other Notes
Small volumes of anti-H2afx antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for H2afx. It may not necessarily be applicable to this product.
NCBI Official Full Name
histone H2AX
NCBI Official Synonym Full Names
H2A histone family, member X
NCBI Official Symbol
H2afx
NCBI Official Synonym Symbols
H2ax; H2A.X; AW228881; Hist5-2ax; gammaH2ax
UniProt Protein Name
Histone H2AX
UniProt Synonym Protein Names
Histone H2A.X
UniProt Gene Name
H2afx
UniProt Synonym Gene Names
H2a.x; H2ax; Hist5-2ax; H2a/x
NCBI Protein Information
histone H2AX
NCBI Summary for H2afx
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. [provided by RefSeq, Nov 2015]
Show more UniProt Comments for H2afx
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Show more Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-H2afx antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| ATM Mediated Phosphorylation Of Repair Proteins Pathway antibodies | ATM Mediated Phosphorylation Of Repair Proteins Pathway Diagram |
| ATM Mediated Response To DNA Double-strand Break Pathway antibodies | ATM Mediated Response To DNA Double-strand Break Pathway Diagram |
| Alcoholism Pathway antibodies | Alcoholism Pathway Diagram |
| Alcoholism Pathway antibodies | Alcoholism Pathway Diagram |
| Assembly Of The RAD50-MRE11-NBS1 Complex At DNA Double-strand Breaks Pathway antibodies | Assembly Of The RAD50-MRE11-NBS1 Complex At DNA Double-strand Breaks Pathway Diagram |
| Cell Cycle Pathway antibodies | Cell Cycle Pathway Diagram |
| Chromosome Maintenance Pathway antibodies | Chromosome Maintenance Pathway Diagram |
| DNA Repair Pathway antibodies | DNA Repair Pathway Diagram |
| Double-Strand Break Repair Pathway antibodies | Double-Strand Break Repair Pathway Diagram |
| Homologous Recombination Repair Pathway antibodies | Homologous Recombination Repair Pathway Diagram |
Diseases associated with anti-H2afx antibody
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >378 publications with H2afx and Neoplasms |
| Ataxia Antibodies | >252 publications with H2afx and Ataxia |
| Carcinoma Antibodies | >122 publications with H2afx and Carcinoma |
| Drug Toxicity Antibodies | >84 publications with H2afx and Drug Toxicity |
| Skin Diseases Antibodies | >68 publications with H2afx and Skin Diseases |
| Breast Neoplasms Antibodies | >66 publications with H2afx and Breast Neoplasms |
| Gastrointestinal Diseases Antibodies | >49 publications with H2afx and Gastrointestinal Diseases |
| Nervous System Diseases Antibodies | >45 publications with H2afx and Nervous System Diseases |
| Lung Neoplasms Antibodies | >44 publications with H2afx and Lung Neoplasms |
| Neoplasms, Experimental Antibodies | >42 publications with H2afx and Neoplasms, Experimental |
Organs/Tissues associated with anti-H2afx antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Lung Antibodies | >63 publications with H2afx and Lung |
| Brain Antibodies | >29 publications with H2afx and Brain |
| Bone Antibodies | >23 publications with H2afx and Bone |
| Liver Antibodies | >15 publications with H2afx and Liver |
| Testis Antibodies | >11 publications with H2afx and Testis |
| Heart Antibodies | >11 publications with H2afx and Heart |
| Intestine Antibodies | >10 publications with H2afx and Intestine |
| Eye Antibodies | >9 publications with H2afx and Eye |
| Embryonic Tissue Antibodies | >9 publications with H2afx and Embryonic Tissue |
| Ovary Antibodies | >7 publications with H2afx and Ovary |


