HRP-Linked Polyclonal Antibody to Parathyroid Hormone Receptor 2 (PTHR2)

Référence MBS2042795-0,5mL

Conditionnement : 0.5mL

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Parathyroid Hormone Receptor 2 (PTHR2) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2042795
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MBS2042795 is an antibody targeting PTHR2. Also known as HRP-Linked Polyclonal Antibody to Parathyroid Hormone Receptor 2 (PTHR2). Reactive in Human, Mouse, Pig. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
Parathyroid Hormone Receptor 2 (PTHR2), Polyclonal Antibody
Full Product Name
HRP-Linked Polyclonal Antibody to Parathyroid Hormone Receptor 2 (PTHR2)
Product Gene Name
anti-PTHR2 antibody
Product Synonym Names
PTH2; PTH2R; Parathyroid Hormone 2 Receptor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Pig
Concentration
500ug/ml (lot specific)
Matching Pairs
Unconjugated Antibody: PTHR2 (MBS2028331)
HRP Conjugated Antibody: PTHR2 (MBS2042795)
Matching Pairs
HRP Conjugated Antibody: PTHR2 (MBS2042795)
Immunogen: PTHR2 (MBS2030688)
Molecular Weight
62,236 Da
OMIM
U25128 mRNA
3D Structure
ModBase 3D Structure for P49190
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Immunogen
PTHR2 (Asp27~Tyr145)
Conjugation
HRP
Cross Reactivity
Human
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2028331
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for anti-PTHR2 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)

Other Notes

Small volumes of anti-PTHR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTHR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
parathyroid hormone 2 receptor isoform 2
NCBI Official Synonym Full Names
parathyroid hormone 2 receptor
NCBI Official Symbol
PTH2R
NCBI Official Synonym Symbols
PTHR2
UniProt Protein Name
Parathyroid hormone 2 receptor
UniProt Gene Name
PTH2R
UniProt Synonym Gene Names
PTHR2; PTH2 receptor
NCBI Protein Information
parathyroid hormone 2 receptor

NCBI Summary for PTHR2

The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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UniProt Comments for PTHR2

PTH2R: This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor. Belongs to the G-protein coupled receptor 2 family.

Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 2q34

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: parathyroid hormone receptor activity; protein binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PTHR2 antibody

 Reference Product  PubMed Publications
 PTH antibody  >19 publications with PTHR2 and PTH
 PTH2 antibody  >7 publications with PTHR2 and PTH2
 PTHLH antibody  >4 publications with PTHR2 and PTHLH

Pathways associated with anti-PTHR2 antibody

 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class B Secretin-like Pathway antibodies  GPCRs, Class B Secretin-like Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram

Diseases associated with anti-PTHR2 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with PTHR2 and Nervous System Diseases
 Brain Diseases Antibodies  >1 publications with PTHR2 and Brain Diseases
 Inflammation Antibodies  >1 publications with PTHR2 and Inflammation
 Seizures Antibodies  >1 publications with PTHR2 and Seizures
 Learning Disorders Antibodies  >1 publications with PTHR2 and Learning Disorders

Organs/Tissues associated with anti-PTHR2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >15 publications with PTHR2 and Brain
 Skin Antibodies  >2 publications with PTHR2 and Skin
 Lung Antibodies  >1 publications with PTHR2 and Lung
 Testis Antibodies  >1 publications with PTHR2 and Testis
 Bone Marrow Antibodies  >1 publications with PTHR2 and Bone Marrow